Hydrogen peroxide and superoxide anion production during acetic acid-induced yeast programmed cell death
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
17702461
DOI
10.1007/bf02931304
Knihovny.cz E-zdroje
- MeSH
- apoptóza fyziologie MeSH
- katalasa metabolismus MeSH
- kyselina octová farmakologie MeSH
- kyseliny farmakologie MeSH
- peroxid vodíku metabolismus MeSH
- Saccharomyces cerevisiae enzymologie fyziologie MeSH
- superoxiddismutasa metabolismus MeSH
- superoxidy metabolismus MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- katalasa MeSH
- kyselina octová MeSH
- kyseliny MeSH
- peroxid vodíku MeSH
- superoxiddismutasa MeSH
- superoxidy MeSH
Hydrogen peroxide production in yeast cells undergoing programmed cell death in response to acetic acid occurred in the majority of live cells 15 min after death induction and was no longer detectable after 60 min. Superoxide anion production was found later, 60 and 90 min after death induction when cells viability was 60 and 30%, respectively. In cells protected from death due to acid stress adaptation neither hydrogen peroxide nor superoxide anion could be observed after acetic acid treatment. The early production of hydrogen peroxide in cells in which survival was 100% could play a major role in acetic acid-induced programmed cell death signaling. Superoxide anion is assumed to be generated in cells already en route to acetic acid-induced programmed cell death.
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