Prevalence of genes encoding extracellular virulence factors among meticillin-resistant Staphylococcus aureus isolates from the University Hospital, Olomouc, Czech Republic
Language English Country Great Britain, England Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
18349356
DOI
10.1099/jmm.0.47413-0
Knihovny.cz E-resources
- MeSH
- Anti-Bacterial Agents pharmacology MeSH
- Bacterial Proteins genetics MeSH
- DNA, Bacterial analysis isolation & purification MeSH
- Virulence Factors genetics MeSH
- Humans MeSH
- Microbial Sensitivity Tests MeSH
- Hospitals, University * MeSH
- Polymerase Chain Reaction MeSH
- Prevalence MeSH
- Electrophoresis, Gel, Pulsed-Field MeSH
- Methicillin Resistance * MeSH
- Staphylococcal Infections epidemiology microbiology MeSH
- Staphylococcus aureus drug effects genetics isolation & purification pathogenicity MeSH
- Virulence genetics MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Czech Republic epidemiology MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
- Bacterial Proteins MeSH
- DNA, Bacterial MeSH
- Virulence Factors MeSH
A rather fast and complicated progression of an infection caused by some strains of Staphylococcus aureus could be associated with the expression and co-action of virulence factor complexes in these strains. This study screened the antibiotic susceptibility and prevalence of virulence markers in isolates of meticillin-resistant S. aureus (MRSA) obtained from patients hospitalized at the University Hospital in Olomouc, Czech Republic. A total of 100 isolates was screened for 13 genes encoding extracellular virulence determinants (tst, pvl, eta, etb, sea, seb, sec, sed, see, seg, seh, sei and sej) and for their distribution in sample types. Eighty-nine isolates were positive for at least one of the genes. Genes for etb, pvl, see and seh were not detected in any of the MRSA isolates. No statistically significant differences in the occurrence of the determinants studied among sample types were found.
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