Antimicrobial resistance and presence of ileS-2 gene encoding mupirocin resistance in clinical isolates of methicillin-resistant Staphylococcus sp
Language English Country United States Media print-electronic
Document type Journal Article
- MeSH
- Anti-Bacterial Agents pharmacology MeSH
- Drug Resistance, Bacterial * MeSH
- Bacterial Proteins genetics MeSH
- Isoleucine-tRNA Ligase genetics MeSH
- Coagulase metabolism MeSH
- Humans MeSH
- Methicillin-Resistant Staphylococcus aureus drug effects enzymology genetics MeSH
- Mupirocin pharmacology MeSH
- Methicillin Resistance MeSH
- Staphylococcal Infections drug therapy microbiology MeSH
- Staphylococcus drug effects enzymology genetics MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
- Bacterial Proteins MeSH
- Isoleucine-tRNA Ligase MeSH
- Coagulase MeSH
- Mupirocin MeSH
Seventy-eight staphylococcal strains were isolated from surgical-site, blood-stream and other hospital-acquired infections. Eighteen isolates were determined as methicillin (MET)-resistant S. aureus (MRSA), while the remaining were MET-resistant coagulase-negative staphylococci (CoNS). Fifty percent of CoNS strains were multiresistant, while 10 % of isolates were resistant only to beta-lactams. Clinical isolates of CoNS were generally more resistant to antimicrobial agents than S. aureus strains. Thirty-nine % of S. aureus strains were resistant only to beta-lactams. None of the MRSA strains carried ileS-2 gene; this gene was found in two strains of S. epidermidis.
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