Urgent termination of pregnancy in pre-eclampsia and panel of antiphospholipid antibodies
Jazyk angličtina Země Dánsko Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
19895376
DOI
10.1111/j.1600-0897.2009.00759.x
PII: AJI759
Knihovny.cz E-zdroje
- MeSH
- antifosfolipidové protilátky krev MeSH
- beta-2-glykoprotein I imunologie MeSH
- dospělí MeSH
- ELISA MeSH
- fosfoserin imunologie MeSH
- lidé MeSH
- placentární oběh imunologie MeSH
- potrat léčebný MeSH
- preeklampsie krev imunologie patofyziologie terapie MeSH
- těhotenství MeSH
- trombóza MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- antifosfolipidové protilátky MeSH
- beta-2-glykoprotein I MeSH
- fosfoserin MeSH
PROBLEM: The present work was undertaken to investigate the occurence of autoantibodies to eight various phospholipids in time of urgent termination of the pregnancy (sectio caesarea) in patients in reproductive age with severe preeclamptic symptoms. METHOD OF STUDY: Autoantibodies against annexin V, ph-serine, ph-ethanolamine, ph-inositol, ph-DL-glycerol, cardiolipin, beta2-glycoprotein I (beta2-GPI), and phosphatidic acid were studied by ELISA methods. RESULTS: Increased levels of IgA-beta2-glycoprotein I, IgG-beta2-glycoprotein I, IgG- anti-ph-serine, and IgG-anticardiolipin were found in sera of preeclamptic women in the time of urgent sectio caesarea when compared to the control group with physiological pregnancy. CONCLUSION: Supposed increase in various antiphospholipid antibodies (aPLs) levels due to the stress during the short time of admission and a need for a quick medical decision to terminate the pregnancy was not unambiguously proven, but our results are evidently influenced by the current urgent life-saving treatment.
Citace poskytuje Crossref.org
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