Changes in the incidence of periodontal pathogens during long-term monitoring and after application of antibacterial drugs
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
- MeSH
- antibakteriální látky terapeutické užití MeSH
- časové faktory MeSH
- dospělí MeSH
- gramnegativní bakteriální infekce diagnóza farmakoterapie epidemiologie mikrobiologie MeSH
- gramnegativní bakterie účinky léků izolace a purifikace MeSH
- incidence MeSH
- lidé středního věku MeSH
- lidé MeSH
- monitorování léčiv * MeSH
- nemoci parodontu diagnóza farmakoterapie epidemiologie mikrobiologie MeSH
- studie případů a kontrol MeSH
- ústa mikrobiologie MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- antibakteriální látky MeSH
The incidence of potential periodontal pathogens (Aggregatibacter actinomycetemcomitans, formerly Actinobacillus actinomycetemcomitans, Tannerella forsythia, Porphyromonas gingivalis, Prevotella nigrescens, Prevotella intermedia and Capnocytophaga ochracea) was monitored in patients with chronic periodontitis and in healthy control subjects. Two types of studies were carried out in which the composition of the bacterial communities in different niches of the same oral cavity ecosystem was investigated. Fluctuation or at least pronounced quantitative changes in the incidence of individual species in time were documented in the long-term study as well as after the local administration of antibacterial drug Chlo-Site or Metronidazole. Even within two weeks, a turnover of the monitored bacteria in separate niches of the oral biotope can be detected. A relatively high incidence of the tested periopathogens in the clinically healthy teeth of patients implies that even the "healthy" niches in the periodontal biotope function as a dynamic reservoir of periopathogenic microorganisms. This should be kept in mind when a local application of antibacterial compounds is used in the therapy of periodontal disease.
Zobrazit více v PubMed
Periodontol 2000. 2004;36:14-26 PubMed
Microbiol Mol Biol Rev. 2007 Dec;71(4):653-70 PubMed
Antimicrob Agents Chemother. 2006 Nov;50(11):3651-7 PubMed
J Clin Periodontol. 2001 Jul;28(7):697-700 PubMed
Eur J Oral Sci. 2006 Feb;114(1):58-63 PubMed
J Clin Periodontol. 2002 Nov;29(11):1023-8 PubMed
Infect Immun. 1994 May;62(5):1889-95 PubMed
J Oral Maxillofac Surg. 2006 Aug;64(8):1303-9 PubMed
Periodontol 2000. 1993 Jun;2:57-71 PubMed
J Clin Periodontol. 2004 Dec;31(12):1034-47 PubMed
Periodontol 2000. 1994 Jun;5:78-111 PubMed
J Clin Microbiol. 1999 Nov;37(11):3504-8 PubMed
Oral Microbiol Immunol. 1996 Aug;11(4):266-73 PubMed
Arch Oral Biol. 2004 Apr;49(4):295-304 PubMed
Nucleic Acids Res. 2002 Aug 1;30(15):3481-9 PubMed
Ann Periodontol. 1996 Nov;1(1):216-22 PubMed
FEMS Microbiol Lett. 2007 Jun;271(1):90-7 PubMed
