Soucasny pohled na problematiku rezistence kmenu Helicobacter pylori vuci antimikrobnim lecivum
[Current perspective of the resistance of Helicobacter pylori strains to antimicrobial drugs]

. 2010 Dec ; 16 (6) : 199-202.

Jazyk čeština Země Česko Médium print

Typ dokumentu časopisecké články, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/pmid21243598
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PubMed 21243598

A significant increase in H. pylori resistance to clarithromycin and metronidazole has been proven in both children and adults. Clarithromycin with resistance over 20 % and metronidazole with resistance over 40 % are not recommended for treating H. pylori infection. Preferred treatment regimens were designed to reflect the current situation. The classical regimen PPI + AMO + CLA (MET) can be used in cases where the resistance against CLA and MET is lower than stated above. In the opposite case, a combination of PPI + AMO + levofloxacin (or rifabutin, or furazolidone) must be used. In many countries, this regimen is already the first-choice treatment. The 4-combination with bismuth is suitable in case of 3-combination treatment failure, or in patients allergic to penicillin.

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