The role of diclofenac and piritramide in the management of acute postoperative pain in hernioplasty
Jazyk angličtina Země Slovensko Médium print
Typ dokumentu srovnávací studie, časopisecké články, práce podpořená grantem
PubMed
21384749
Knihovny.cz E-zdroje
- MeSH
- antiflogistika nesteroidní terapeutické užití MeSH
- diklofenak terapeutické užití MeSH
- inguinální hernie chirurgie MeSH
- lidé středního věku MeSH
- lidé MeSH
- měření bolesti MeSH
- opioidní analgetika terapeutické užití MeSH
- pirinitramid terapeutické užití MeSH
- pooperační bolest farmakoterapie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
- Názvy látek
- antiflogistika nesteroidní MeSH
- diklofenak MeSH
- opioidní analgetika MeSH
- pirinitramid MeSH
OBJECTIVES: The aim of the study was to compare the effects of diclofenac and piritramide in acute postoperative pain after hernioplasty. BACKGROUND: In the treatment of moderate acute postoperative pain, non-steroidal anti-inflammatory drugs and opioids play the major role. The data on safety and effect of analgesia based on opioid and non-opioid drugs are still a controversial topic. METHODS: We compared the first-line treatment effects of diclofenac and piritramide in 105 patients after hernioplasty in a retrospective manner. The subsequent therapy combined piritramide with diclofenac. We evaluated the intensity of pain and its relief using a visual analogue scale (VAS). We also evaluated the necessity of application of other analgesics. RESULTS: One hour after the application of the first analgesic dose, we observed complete pain relief in 39.5% of patients treated with piritramide and in 19.4% of patients treated with diclofenac (chi2=5.17; p=0.02). After the use of piritramide, the pain relief (3.84 +/- 1.27 mm) was significantly higher than after diclofenac (3.34 +/- 0.77 mm). Another injection was needed in 76% and 54% of patients subjected to first-line treatment based on diclofenac and piritramide, respectively. CONCLUSION: We observed that the first-line analgesic treatment based on piritramide was more effective when compared to that based on diclofenac (Tab. 3, Ref. 3). Full Text in free PDF www.bmj.sk.