Compounded preparations with nystatin for oral and oromucosal administration
Jazyk angličtina Země Polsko Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
23923400
Knihovny.cz E-zdroje
- MeSH
- antifungální látky aplikace a dávkování chemie MeSH
- aplikace bukální MeSH
- aplikace orální MeSH
- deriváty hypromelózy MeSH
- farmaceutická chemie MeSH
- farmaceutická technologie metody MeSH
- glycerol chemie MeSH
- hydrogely MeSH
- kandidóza farmakoterapie mikrobiologie MeSH
- lidé MeSH
- methylcelulosa analogy a deriváty chemie MeSH
- nystatin aplikace a dávkování chemie MeSH
- příprava léků MeSH
- viskozita MeSH
- xylitol chemie MeSH
- želatina chemie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- antifungální látky MeSH
- deriváty hypromelózy MeSH
- glycerol MeSH
- hydrogely MeSH
- methylcelulosa MeSH
- nystatin MeSH
- xylitol MeSH
- želatina MeSH
Therapy of oral, esophageal and gastrointestinal candidiasis is still a common problem that can be solved by an administration of antimycotics. Major disadvantage of registered commercial antifungal medicinal products is their price, so the health care system and its payers may profit from extemporaneous compounding. An appropriate drug therapy for candidiasis (trush) is nystatin, which is a substance available in the Czech Republic for the magistral preparation relatively recently, since 2010. Making formulas for extemporaneous compounding is quite simple and preparations particularly useful for dentists, pediatricians, otolaryngologists, oncologists and gastroenterologists. The authors formulated composition of viscous oromucosal suspension, oral/oromucosal hydrogel and oromucosal gelatine globule which may be present as compounded products containing nystatin for oromucosal and/or oral administration. The preparation is practically verified and magistral products have been already used in clinical practice.
