Cryogenic grinding of electrospun poly-ε-caprolactone mesh submerged in liquid media
Language English Country Netherlands Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
24364933
DOI
10.1016/j.msec.2012.04.012
PII: S0928-4931(12)00131-2
Knihovny.cz E-resources
- MeSH
- Cell Adhesion drug effects MeSH
- Cell Line MeSH
- 3T3 Cells MeSH
- Fibroblasts drug effects MeSH
- Microscopy, Electron, Scanning methods MeSH
- Mice MeSH
- Nanoparticles chemistry MeSH
- Polyesters chemistry pharmacology MeSH
- Cell Proliferation drug effects MeSH
- Cell Survival drug effects MeSH
- Animals MeSH
- Check Tag
- Mice MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- polycaprolactone MeSH Browser
- Polyesters MeSH
In this paper, the treatment of poly-ε-caprolactone (PCL) nano/micro-mesh system by cryogenic grinding and subsequent characterization of obtained product is described. The PCL nano/micro-mesh layer submerged in appropriate liquid was cryogenically ground and obtained particles were characterized employing mainly laser diffraction and scanning electron microscopy (SEM). In the ground sample, different types of particles (fibrous particles, fibrous fragments, agglomerates with and without an internal fibrous structure, lamellae and nanoparticles) were identified, described and quantified. Parameters of cryogenic grinding (weight of sample, type of liquid medium, and influence of sample storage) were optimized to maximize the yield of particles with desired features. The potential of the system for cell scaffolding was demonstrated by cultivation of 3T3 fibroblasts on the produced microparticles.
References provided by Crossref.org
Nanofiber Fractionalization Stimulates Healing of Large Intestine Anastomoses in Rabbits
Nanofibrous polycaprolactone scaffolds with adhered platelets stimulate proliferation of skin cells
