Effect of catheter-based patent foramen ovale closure on the occurrence of arterial bubbles in scuba divers
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu časopisecké články, pozorovací studie, práce podpořená grantem
PubMed
24630875
DOI
10.1016/j.jcin.2013.12.199
PII: S1936-8798(14)00445-2
Knihovny.cz E-zdroje
- Klíčová slova
- catheter-based closure, decompression sickness, paradoxical embolization, patent foramen ovale,
- MeSH
- časové faktory MeSH
- dekompresní nemoc diagnostické zobrazování etiologie prevence a kontrola MeSH
- dospělí MeSH
- echokardiografie transezofageální MeSH
- foramen ovale apertum diagnostické zobrazování terapie MeSH
- lidé středního věku MeSH
- lidé MeSH
- potápění škodlivé účinky MeSH
- prediktivní hodnota testů MeSH
- rizikové faktory MeSH
- septální okluder MeSH
- srdeční katetrizace * přístrojové vybavení MeSH
- studie případů a kontrol MeSH
- ultrasonografie dopplerovská transkraniální MeSH
- výsledek terapie MeSH
- vzduchová embolie diagnostické zobrazování etiologie prevence a kontrola MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- pozorovací studie MeSH
- práce podpořená grantem MeSH
OBJECTIVES: This study sought to evaluate the effect of catheter-based patent foramen ovale (PFO) closure on the occurrence of arterial bubbles after simulated dives. BACKGROUND: PFO is a risk factor of decompression sickness in divers due to paradoxical embolization of bubbles. To date, the effectiveness of catheter-based PFO closure in the reduction of arterial bubbles has not been demonstrated. METHODS: A total of 47 divers (age 35.4 ± 8.6 years, 81% men) with a PFO (PFO group) or treated with a catheter-based PFO closure (closure group) were enrolled in this case-controlled observational trial. All divers were examined after a simulated dive in a hyperbaric chamber: 34 divers (19 in the PFO group, 15 in the closure group) performed a dive to 18 m for 80 min, and 13 divers (8 in the PFO group, 5 in the closure group) performed a dive to 50 m for 20 min. Within 60 min after surfacing, the presence of venous and arterial bubbles was assessed by transthoracic echocardiography and transcranial color-coded sonography, respectively. RESULTS: After the 18-m dive, venous bubbles were detected in 74% of divers in the PFO group versus 80% in the closure group (p = 1.0), and arterial bubbles were detected in 32% versus 0%, respectively (p = 0.02). After the 50-m dive, venous bubbles were detected in 88% versus 100%, respectively (p = 1.0), and arterial bubbles were detected in 88% versus 0%, respectively (p < 0.01). CONCLUSIONS: No difference was observed in the occurrence of venous bubbles between the PFO and closure groups, but the catheter-based PFO closure led to complete elimination of arterial bubbles after simulated dives. (Nitrogen Bubble Detection After Simulated Dives in Divers With PFO and After PFO Closure; NCT01854281).
Cardiocentrum Hospital Podlesí Třinec Czech Republic
Hyperbaric Chamber Kladno Regional Hospital Kladno Czech Republic
Citace poskytuje Crossref.org
ClinicalTrials.gov
NCT01854281
