Effect of catheter-based patent foramen ovale closure on the occurrence of arterial bubbles in scuba divers
Language English Country United States Media print-electronic
Document type Journal Article, Observational Study, Research Support, Non-U.S. Gov't
PubMed
24630875
DOI
10.1016/j.jcin.2013.12.199
PII: S1936-8798(14)00445-2
Knihovny.cz E-resources
- Keywords
- catheter-based closure, decompression sickness, paradoxical embolization, patent foramen ovale,
- MeSH
- Time Factors MeSH
- Decompression Sickness diagnostic imaging etiology prevention & control MeSH
- Adult MeSH
- Echocardiography, Transesophageal MeSH
- Foramen Ovale, Patent diagnostic imaging therapy MeSH
- Middle Aged MeSH
- Humans MeSH
- Diving adverse effects MeSH
- Predictive Value of Tests MeSH
- Risk Factors MeSH
- Septal Occluder Device MeSH
- Cardiac Catheterization * instrumentation MeSH
- Case-Control Studies MeSH
- Ultrasonography, Doppler, Transcranial MeSH
- Treatment Outcome MeSH
- Embolism, Air diagnostic imaging etiology prevention & control MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Observational Study MeSH
- Research Support, Non-U.S. Gov't MeSH
OBJECTIVES: This study sought to evaluate the effect of catheter-based patent foramen ovale (PFO) closure on the occurrence of arterial bubbles after simulated dives. BACKGROUND: PFO is a risk factor of decompression sickness in divers due to paradoxical embolization of bubbles. To date, the effectiveness of catheter-based PFO closure in the reduction of arterial bubbles has not been demonstrated. METHODS: A total of 47 divers (age 35.4 ± 8.6 years, 81% men) with a PFO (PFO group) or treated with a catheter-based PFO closure (closure group) were enrolled in this case-controlled observational trial. All divers were examined after a simulated dive in a hyperbaric chamber: 34 divers (19 in the PFO group, 15 in the closure group) performed a dive to 18 m for 80 min, and 13 divers (8 in the PFO group, 5 in the closure group) performed a dive to 50 m for 20 min. Within 60 min after surfacing, the presence of venous and arterial bubbles was assessed by transthoracic echocardiography and transcranial color-coded sonography, respectively. RESULTS: After the 18-m dive, venous bubbles were detected in 74% of divers in the PFO group versus 80% in the closure group (p = 1.0), and arterial bubbles were detected in 32% versus 0%, respectively (p = 0.02). After the 50-m dive, venous bubbles were detected in 88% versus 100%, respectively (p = 1.0), and arterial bubbles were detected in 88% versus 0%, respectively (p < 0.01). CONCLUSIONS: No difference was observed in the occurrence of venous bubbles between the PFO and closure groups, but the catheter-based PFO closure led to complete elimination of arterial bubbles after simulated dives. (Nitrogen Bubble Detection After Simulated Dives in Divers With PFO and After PFO Closure; NCT01854281).
Cardiocentrum Hospital Podlesí Třinec Czech Republic
Hyperbaric Chamber Kladno Regional Hospital Kladno Czech Republic
References provided by Crossref.org
ClinicalTrials.gov
NCT01854281
