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Záznam pochází z PubMed

Weight loss maintenance in overweight subjects on ad libitum diets with high or low protein content and glycemic index: the DIOGENES trial 12-month results

Aller, E E J G
Autor Aller, E E J G Department of Human Biology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands
Larsen, T M
Autor Larsen, T M Department of Nutrition, Exercise and Sports (NEXS), Faculty of Science, University of Copenhagen, Copenhagen, Denmark
Claus, H
Autor Claus, H Institute of Preventive Medicine, Centre for Health and Society, Copenhagen, Denmark
Lindroos, A K
Autor Lindroos, A K MRC Human Nutrition Research, Elsie Widdowson Laboratory, Cambridge, UK
Kafatos, A
Autor Kafatos, A Department of Social Medicine, Preventive Medicine & Nutrition Clinic, University of Crete, Heraklion, Greece
Pfeiffer, A
Autor Pfeiffer, A Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuhetal, Germany
Martinez, J A
Autor Martinez, J A ] Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain [2] CIBERObn, Instituto Carlos III, Madrid, Spain
Handjieva-Darlenska, T
Autor Handjieva-Darlenska, T National Multiprofile Transport Hospital, Sofia, Bulgaria
Kunesova, M
Autor Kunesova, M Obesity Management Centre, Institute of Endocrinology, Prague, Czech Republic
Stender, S
Autor Stender, S Department of Clinical Biochemistry, Gentofte University Hospital, Hellerup, Denmark
Saris, W H M
Autor Saris, W H M Department of Human Biology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands
Astrup, A
Autor Astrup, A Department of Nutrition, Exercise and Sports (NEXS), Faculty of Science, University of Copenhagen, Copenhagen, Denmark
van Baak, M A
Autor van Baak, M A Department of Human Biology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands

International journal of obesity (2005). 2014 Dec ; 38 (12) : 1511-7. [epub] 20140328

Int J Obes (Lond)
ISSN 1476-5497 | 0307-0565
Zdroj

Jazyk angličtina Země Velká Británie, Anglie Médium print-electronic

Typ dokumentu časopisecké články, multicentrická studie, randomizované kontrolované studie, práce podpořená grantem

Perzistentní odkaz https://www.medvik.cz/link/pmid24675714

PubMed 24675714
DOI 10.1038/ijo.2014.52
PII: ijo201452
Knihovny.cz E-zdroje

MeSH
adherence pacienta MeSH
běloši * MeSH
časové faktory MeSH
dietní proteiny aplikace a dávkování MeSH
dietní sacharidy aplikace a dávkování MeSH
dospělí MeSH
energetický příjem MeSH
glukózový toleranční test MeSH
glykemický index * MeSH
hmotnostní přírůstek * MeSH
hmotnostní úbytek * MeSH
index tělesné hmotnosti MeSH
kalorická restrikce MeSH
lidé MeSH
nízkoproteinová dieta MeSH
obezita prevence a kontrola terapie MeSH
obvod pasu MeSH
redukční dieta * MeSH
rodina MeSH
tělesná hmotnost MeSH
výživa - přehledy MeSH
Check Tag
dospělí MeSH
lidé MeSH
mužské pohlaví MeSH
ženské pohlaví MeSH
Publikační typ
časopisecké články MeSH
multicentrická studie MeSH
práce podpořená grantem MeSH
randomizované kontrolované studie MeSH
Geografické názvy
Evropa epidemiologie MeSH
Názvy látek
dietní proteiny MeSH
dietní sacharidy MeSH

BACKGROUND: A high dietary protein (P) content and low glycemic index (LGI) have been suggested to be beneficial for weight management, but long-term studies are scarce. OBJECTIVE: The DIOGENES randomized clinical trial investigated the effect of P and GI on weight loss maintenance in overweight or obese adults in eight centers across Europe. This study reports the 1-year results in two of the centers that extended the intervention to 1 year. METHOD: After an 8-week low-calorie diet (LCD), 256 adults (body mass index >27 kg m(-)(2)) were randomized to five ad libitum diets for 12 months: high P/LGI (HP/LGI), HP/high GI (HP/HGI), low P/LGI (LP/LGI), LP/HGI and a control diet. During the first 6 months, foods were provided for free through a shop system and during the whole 12-month period, subjects received guidance by a dietician. Primary outcome variable was the change in body weight over the 12-month intervention period. RESULTS: During the LCD period, subjects lost 11.2 (10.8, 12.0) kg (mean (95% confidence interval (CI))). Average weight regain over the 12-month intervention period was 3.9 (95% CI 3.0-4.8) kg. Subjects on the HP diets regained less weight than subjects on the LP diets. The difference in weight regain after 1 year was 2.0 (0.4, 3.6) kg (P=0.017) (completers analysis, N=139) or 2.8 (1.4, 4.1) kg (P<0.001) (intention-to-treat analysis, N=256). No consistent effect of GI on weight regain was found. There were no clinically relevant differences in changes in cardiometabolic risk factors among diet groups. CONCLUSION: A higher protein content of an ad libitum diet improves weight loss maintenance in overweight and obese adults over 12 months.

] Department of Physiology and Nutrition University of Navarra Pamplona Spain [2] CIBERObn Instituto Carlos 3 Madrid Spain

Department of Clinical Biochemistry Gentofte University Hospital Hellerup Denmark

Department of Clinical Nutrition German Institute of Human Nutrition Potsdam Rehbruecke Nuhetal Germany

Department of Human Biology NUTRIM School for Nutrition Toxicology and Metabolism Maastricht University Medical Centre Maastricht The Netherlands

Department of Nutrition Exercise and Sports Faculty of Science University of Copenhagen Copenhagen Denmark

Department of Social Medicine Preventive Medicine and Nutrition Clinic University of Crete Heraklion Greece

Institute of Preventive Medicine Centre for Health and Society Copenhagen Denmark

MRC Human Nutrition Research Elsie Widdowson Laboratory Cambridge UK

National Multiprofile Transport Hospital Sofia Bulgaria

Obesity Management Centre Institute of Endocrinology Prague Czech Republic

Zobrazit více v PubMed

Nutr Metab Cardiovasc Dis. 2013 Aug;23(8):699-706 PubMed