Kazuistika pacienta se značně pokročilým a diseminovaným karcinomem žaludku léčeným preparátem S-1
[Case report of a patient with advanced and disseminated gastric carcinoma treated by s-1]

. 2014 ; 27 (3) : 207-9.

Jazyk čeština Země Česko Médium print

Typ dokumentu kazuistiky, anglický abstrakt, časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/pmid24918280
Odkazy

PubMed 24918280
DOI 10.14735/amko2014207
PII: 48822

BACKGROUND: Prognosis of patients with metastatic gastric cancer is abysmal, usually just a few months. S-1 is a peroral fluoropyrimidine antitumor drug. It is a fixed combination of three effective drugs - tegafur, gimeracil and oteracil potassium. CASE: This is a case report of a 71-year-old man treated for local advanced and metastatic gastric carcinoma treated with combination of S-1 and cisplatin as a first line of therapy. Treatment response reached partial remission and lasted for six months. Treatment was very well tolerated, with no grade 3 and 4 toxicity. After progression, the patient was treated with further lines of therapy. CONCLUSION: In the Czech Republic, experience with S-1 drug is very limited. Our case report showed a good treatment response and minimal toxicity of this treatment, in concordance with results of the study FLAGS.

Citace poskytuje Crossref.org

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