Outcomes and their predictors in lumbar spinal stenosis: a 12-year follow-up
Jazyk angličtina Země Německo Médium print-electronic
Typ dokumentu časopisecké články, pozorovací studie
- MeSH
- bederní obratle * patofyziologie chirurgie MeSH
- komorbidita MeSH
- lidé středního věku MeSH
- lidé MeSH
- logistické modely MeSH
- následné studie MeSH
- prospektivní studie MeSH
- senioři MeSH
- spinální stenóza epidemiologie patofyziologie chirurgie MeSH
- výsledek terapie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- pozorovací studie MeSH
PURPOSE: The aim of this prospective observational cohort study was to evaluate long-term outcomes in patients with mild-to-moderate lumbar spinal stenosis (LSS) and to analyse the predictors of clinical outcomes. METHODS: A group of 53 patients were re-examined after a median period of 139 months. Evaluations were made of subjective clinical outcome, objective clinical outcome and its predictors, any correlation between subjective and objective outcome, and the development of changes in radiological and electrophysiological parameters after 12 years. RESULTS: Satisfactory objective and subjective clinical outcomes were recorded in 54.7 and 43.4% of patients, respectively. No statistically significant correlation between objective and subjective clinical outcome was found (Spearman coefficient = 0.225, p = 0.132). Patients with isolated unsatisfactory subjective outcome exhibited the highest Functional Comorbidity Index of all subgroups. Electrophysiological and radiological findings did not demonstrate statistically significant changes after 12-year follow-up. Multivariate logistic regression confirmed only the lowest transverse diameter of spinal canal ≦13.6 mm as an independent predictor of unsatisfactory clinical outcome (OR = 5.51). CONCLUSIONS: Satisfactory objective and subjective clinical outcomes were disclosed in about half of the patients with mild-to-moderate LSS in a 12-year follow-up. The number of comorbid diseases had an unfavourable effect on subjective evaluation of clinical outcome. The lowest transverse diameter of spinal canal proved to be the only independent predictor of deterioration of clinical status in LSS patients.
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Spine (Phila Pa 1976). 2005 Apr 15;30(8):936-43 PubMed
Spine (Phila Pa 1976). 1995 May 15;20(10):1155-60 PubMed
Spine (Phila Pa 1976). 2000 Jun 1;25(11):1424-35; discussion 1435-6 PubMed
Spine (Phila Pa 1976). 2012 Oct 1;37(21):1791-802 PubMed
Nat Rev Neurol. 2009 Jul;5(7):392-403 PubMed
Spine J. 2013 Jul;13(7):734-43 PubMed
Eur Spine J. 2013 Apr;22(4):953-74 PubMed
Spine (Phila Pa 1976). 2010 Jun 15;35(14):1329-38 PubMed
Eur Spine J. 2012 Mar;21(3):411-7 PubMed
Spine (Phila Pa 1976). 2007 Jan 1;32(1):1-8 PubMed
Eur Spine J. 2013 Sep;22(9):2010-4 PubMed
Spine J. 2011 Jul;11(7):613-7 PubMed
Spine (Phila Pa 1976). 2006 Aug 15;31(18):E648-63 PubMed
Joint Bone Spine. 2002 Oct;69(5):450-7 PubMed
Spine (Phila Pa 1976). 2006 Dec 1;31(25):2950-7 PubMed
Spine (Phila Pa 1976). 2000 Mar 1;25(5):556-62 PubMed
Eur Spine J. 2012 May;21(5):825-8 PubMed
J Spinal Disord. 1998 Apr;11(2):110-5 PubMed
Eur Spine J. 2013 Aug;22(8):1897-906 PubMed
Spine (Phila Pa 1976). 2000 Jan 15;25(2):197-203; discussions 203-4 PubMed
Acta Orthop. 2012 Oct;83(5):536-42 PubMed
Clin Orthop Relat Res. 1992 Jun;(279):82-6 PubMed
Eur Spine J. 2007 Feb;16(2):199-206 PubMed
Eur Spine J. 2011 Jul;20(7):1174-81 PubMed
Spine (Phila Pa 1976). 1996 Aug 1;21(15):1787-94; discussion 1794-5 PubMed
N Engl J Med. 2008 Feb 21;358(8):794-810 PubMed
J Clin Epidemiol. 2005 Jun;58(6):595-602 PubMed
Eur Spine J. 2012 Dec;21(12):2611-9 PubMed
Spine (Phila Pa 1976). 2011 Sep 15;36(20):E1335-51 PubMed
