Superhydrophilic polystyrene nanofiber materials generating O2((1)Δ(g)): postprocessing surface modifications toward efficient antibacterial effect
Language English Country United States Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
25014212
DOI
10.1021/am502917w
Knihovny.cz E-resources
- MeSH
- Anti-Bacterial Agents pharmacology MeSH
- Time Factors MeSH
- Diffusion drug effects MeSH
- Escherichia coli drug effects growth & development MeSH
- Spectrometry, Fluorescence MeSH
- Hydrophobic and Hydrophilic Interactions * MeSH
- Kinetics MeSH
- Microbial Sensitivity Tests MeSH
- Nanofibers chemistry ultrastructure MeSH
- Oxidation-Reduction drug effects MeSH
- Permeability drug effects MeSH
- Colony Count, Microbial MeSH
- Polystyrenes chemistry MeSH
- Surface Properties MeSH
- Singlet Oxygen pharmacology MeSH
- Spectrophotometry, Ultraviolet MeSH
- Spectroscopy, Fourier Transform Infrared MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
- Polystyrenes MeSH
- Singlet Oxygen MeSH
The surfaces of electrospun polystyrene (PS) nanofiber materials with encapsulated 1% w/w 5,10,15,20-tetraphenylporphyrin (TPP) photosensitizer were modified through sulfonation, radio frequency (RF) oxygen plasma treatment, and polydopamine coating. The nanofiber materials exhibited efficient photogeneration of singlet oxygen. The postprocessing modifications strongly increased the wettability of the pristine hydrophobic PS nanofibers without causing damage to the nanofibers, leakage of the photosensitizer, or any substantial change in the oxygen permeability of the inner bulk of the polymer nanofiber. The increase in the surface wettability yielded a significant increase in the photo-oxidation of external polar substrates and in the antibacterial activity of the nanofibers in aqueous surroundings. The results reveal the crucial role played by surface hydrophilicity/wettability in achieving the efficient photo-oxidation of a chemical substrate/biological target at the surface of a material generating O2((1)Δg) with a short diffusion length.
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