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PubMed

Záznam pochází z PubMed

Allogeneic and autologous stem cell transplantation for hepatosplenic T-cell lymphoma: a retrospective study of the EBMT Lymphoma Working Party

Tanase, A
Autor Tanase, A ] EBMT Lymphoma Working Party, Paris, France [2] BMT Department, Fundeni Clinical Institute, Fundeni Hospital, Bucharest, Romania
Schmitz, N
Autor Schmitz, N ] EBMT Lymphoma Working Party, Paris, France [2] Department of Hematology and Stem Cell Transplantation, Asklepios Klinik St Georg, Hamburg, Germany
Stein, H
Autor Stein, H Pathodiagnostik Berlin, Berlin, Germany
Boumendil, A
Autor Boumendil, A EBMT Lymphoma Working Party, Paris, France
Finel, H
Autor Finel, H EBMT Lymphoma Working Party, Paris, France
Castagna, L
Autor Castagna, L Humanitas Cancer Center, Rozzano, Italy
Blaise, D
Autor Blaise, D Institut Paoli Calmettes, Marseille, France
Milpied, N
Autor Milpied, N CHU Bordeaux, Bordeaux, France
Sucak, G
Autor Sucak, G Gazi Universitesi Tip Fakultesi, Ankara, Turkey
Sureda, A
Autor Sureda, A ] EBMT Lymphoma Working Party, Paris, France [2] Servei d' Hematologia, Institut Catala d'Oncologia- Hospital Duran i Reynals, Barcelona, Spain
Thomson, K
Autor Thomson, K University College London Hospital, London, UK
Vandenberghe, E
Autor Vandenberghe, E St James's Hospital, Dublin, Ireland
Vitek, A
Autor Vitek, A Institute of Hematology and Blood Transfusion, Prague, Czech Republic
Dreger, P
Autor Dreger, P ] EBMT Lymphoma Working Party, Paris, France [2] Department of Medicine, University of Heidelberg, Heidelberg, Germany
Lymphoma Working Party of the EBMT
Autor Lymphoma Working Party of the EBMT

Leukemia. 2015 Mar ; 29 (3) : 686-8. [epub] 20140919

ISSN 1476-5551 | 0887-6924
Zdroj

Jazyk angličtina Země Velká Británie, Anglie Médium print-electronic

Typ dokumentu časopisecké články

Perzistentní odkaz https://www.medvik.cz/link/pmid25234166

PubMed 25234166
DOI 10.1038/leu.2014.280
PII: leu2014280
Knihovny.cz E-zdroje

MeSH
analýza přežití MeSH
autologní transplantace MeSH
databáze faktografické MeSH
dospělí MeSH
homologní transplantace MeSH
kooperační chování MeSH
lidé středního věku MeSH
lidé MeSH
mladiství MeSH
nádory jater mortalita patologie terapie MeSH
nádory sleziny mortalita patologie terapie MeSH
následné studie MeSH
periferní T-buněčný lymfom mortalita patologie terapie MeSH
recidiva MeSH
registrace * MeSH
retrospektivní studie MeSH
senioři MeSH
transplantace hematopoetických kmenových buněk * MeSH
výsledek terapie MeSH
Check Tag
dospělí MeSH
lidé středního věku MeSH
lidé MeSH
mladiství MeSH
mužské pohlaví MeSH
senioři MeSH
ženské pohlaví MeSH
Publikační typ
časopisecké články MeSH
Geografické názvy
Evropa MeSH

The objective of this registry study was to analyse the outcome of patients who underwent allogeneic or autologous haematopoietic stem cell transplantation (HSCT) for hepatosplenic T-cell lymphoma (HSTL), a rare and extremely aggressive peripheral T-cell lymphoma subtype. Patients were eligible if they had histologically verified HSTL and underwent HSCT between 2003 and 2011. Seventy-six patients were identified in the European Society for Bone and Marrow Transplantation database. Additional baseline and follow-up information could be obtained from the referring centres for 36 patients. Eleven of these were excluded following histopathology review, leaving 25 patients in the final study cohort (alloHSCT 18, autoHSCT 7). With a median follow-up of 36 months, 2 patients relapsed after alloHSCT, resulting in a 3-year progression-free survival of 48%. After autoHSCT, 5 patients relapsed and subsequently died. This study indicates that graft-versus-lymphoma activity conferred by alloHSCT can result in long-term survival for a substantial proportion of patients with HSTL.

] EBMT Lymphoma Working Party Paris France [2] BMT Department Fundeni Clinical Institute Fundeni Hospital Bucharest Romania

] EBMT Lymphoma Working Party Paris France [2] Department of Hematology and Stem Cell Transplantation Asklepios Klinik St Georg Hamburg Germany

] EBMT Lymphoma Working Party Paris France [2] Department of Medicine University of Heidelberg Heidelberg Germany

] EBMT Lymphoma Working Party Paris France [2] Servei d' Hematologia Institut Catala d'Oncologia Hospital Duran i Reynals Barcelona Spain

CHU Bordeaux Bordeaux France

EBMT Lymphoma Working Party Paris France

Gazi Universitesi Tip Fakultesi Ankara Turkey

Humanitas Cancer Center Rozzano Italy

Institut Paoli Calmettes Marseille France

Institute of Hematology and Blood Transfusion Prague Czech Republic

Pathodiagnostik Berlin Berlin Germany

St James's Hospital Dublin Ireland