Maghemite based silicone composite for arterial embolization hyperthermia
Jazyk angličtina Země Nizozemsko Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
25579966
DOI
10.1016/j.msec.2014.12.046
PII: S0928-4931(14)00844-3
Knihovny.cz E-zdroje
- Klíčová slova
- Arterial embolization hyperthermia, Embolic material, Maghemite nanoparticles, Radiopacity, Rheological properties, Specific loss power,
- MeSH
- indukovaná hypertermie * MeSH
- jodid draselný chemie MeSH
- lidé MeSH
- magnetické pole * MeSH
- nanokompozity chemie MeSH
- pružnost MeSH
- silikony chemie MeSH
- terapeutická embolizace * MeSH
- železité sloučeniny chemie MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- ferric oxide MeSH Prohlížeč
- jodid draselný MeSH
- silikony MeSH
- železité sloučeniny MeSH
Maghemite nanoparticle based silicone composite for application in arterial embolization hyperthermia is developed. It possesses embolization ability, high heating efficiency in alternating magnetic fields and radiopaque property. The initial components of the composite are selected so that the material stays liquid for 20min, providing the opportunity for transcatheter transportation and filling of the tumour vascular system. After this induction period the viscosity increases rapidly and soft embolus is formed which is able to occlude the tumour blood vessels. The composite is thermally stable up to 225°C, displays rubber-elastic properties and has a thermal expansion coefficient higher than that of blood. Maghemite nanoparticles uniformly distributed in the composite provide its rapid heating (tens of °Cmin(-1)) due to Neel magnetization relaxation. Required X-ray contrast of composite is achieved by addition of potassium iodide.
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