Streptococcus agalactiae in pregnancies complicated by preterm prelabor rupture of membranes
Jazyk angličtina Země Anglie, Velká Británie Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
- Klíčová slova
- Amniocentesis, amniotic fluid, group B streptococcus, sepsis, vaginal swab,
- MeSH
- dospělí MeSH
- incidence MeSH
- infekční komplikace v těhotenství epidemiologie mikrobiologie MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- nemoci novorozenců epidemiologie mikrobiologie MeSH
- novorozenec MeSH
- plodová voda mikrobiologie MeSH
- předčasný odtok plodové vody mikrobiologie MeSH
- retrospektivní studie MeSH
- sepse epidemiologie mikrobiologie MeSH
- Streptococcus agalactiae izolace a purifikace MeSH
- streptokokové infekce epidemiologie MeSH
- těhotenství MeSH
- vagina mikrobiologie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- novorozenec MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
OBJECTIVE: The main aim of this study was to evaluate the presence of Streptococcus agalactiae (S. agalactiae) in the vagina and the amniotic fluid in pregnancies complicated by preterm prelabor rupture of membranes (PPROM). The next aim was to evaluate the incidence of S. agalactiae early onset sepsis in newborns from PPROM pregnancies, with respect to the presence of S. agalactiae in the vagina and the amniotic fluid. METHODS: Singleton gestations with PPROM between 24 + 0 and 36 + 6 were included. A vaginal swab was obtained, and amniocentesis was performed at admission. The presence of S. agalactiae in the vagina and in the amniotic fluid was assessed by culture and by real-time polymerase chain reaction, respectively. RESULTS: In total, 336 women were included. The presence of S. agalactiae in the vaginal and amniotic fluid was found in 9% (31/336) and 1% (3/336) of women. One woman had S. agalactiae in the amniotic fluid but was negative for the presence of S. agalactiae in the vaginal fluid. Early onset neonatal sepsis developed in one newborn from pregnancies complicated by the presence of S. agalactiae in the amniotic fluid. CONCLUSION: The presence of S. agalactiae in the vagina and amniotic fluid complicated approximately each 10th and each 100th PPROM pregnancy. Cultivation-negative findings of S. agalactiae in the vagina did not exclude the positivity of the amniotic fluid for S. agalactiae and the development of early onset sepsis in newborns.
c Department of Obstetrics and Gynecology Sahlgrenska Academy Gothenburg Sweden
f Biomedical Research Center University Hospital Hradec Kralove Czech Republic
Citace poskytuje Crossref.org
