Antibiotic profiling of Clostridium difficile ribotype 176--A multidrug resistant relative to C. difficile ribotype 027
Language English Country England, Great Britain Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
26256807
DOI
10.1016/j.anaerobe.2015.07.009
PII: S1075-9964(15)30045-7
Knihovny.cz E-resources
- Keywords
- Clostridium difficile, Erythromycin, Moxifloxacin, PCR-ribotype 176, Resistance, Rifampicin, Thr82Ile,
- MeSH
- Anti-Bacterial Agents pharmacology MeSH
- Bacterial Proteins genetics metabolism MeSH
- Clostridioides difficile classification drug effects genetics isolation & purification MeSH
- Humans MeSH
- Drug Resistance, Multiple, Bacterial * MeSH
- Molecular Sequence Data MeSH
- Mutation MeSH
- Enterocolitis, Pseudomembranous microbiology MeSH
- Ribotyping MeSH
- Base Sequence MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Czech Republic MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
- Bacterial Proteins MeSH
Antibiotic profiling of twenty Czech Clostridium difficile PCR-ribotype 176 isolates revealed a high level of resistance to erythromycin, ciprofloxacin and moxifloxacin (n = 20) and to rifampicin (n = 13). Accumulation of resistance mechanisms to multiple antibiotics highlight that PCR-ribotype 176 belong to problematic epidemic strains.
References provided by Crossref.org
