We report that a subset of avian genes is characterized by very high GC content and long G/C stretches. These sequence characteristics correlate with the frequent absence of these genes from genomic databases. We provide several examples where genes in this subset are mistakenly reported as missing in birds. www.dx.doi.org/10.1186/s13059-015-0725-y.

Institute of Molecular Genetics Academy of Sciences of the Czech Republic Vídeňská 1083 14220 Prague Czech Republic

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Genome Biol. 2014;15(12):565. doi: 10.1186/s13059-014-0565-1. PubMed

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Genome Biol. 2015 Aug 18;16:165. doi: 10.1186/s13059-015-0725-y. PubMed

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