miRNA jako nový ukazatel u diabetes mellitus a u rozvoje karcinomu pankreatu
[miRNA as a new marker of diabetes mellitus and pancreatic carcinoma progression]
Jazyk čeština Země Česko Médium print
Typ dokumentu časopisecké články, přehledy
PubMed
26311027
PII: 52950
- Klíčová slova
- diabetes mellitus - miRNA - pancreatic cancer - chronic pancreatitis.,
- MeSH
- chronická pankreatitida genetika MeSH
- diabetes mellitus diagnóza genetika MeSH
- genetické markery genetika MeSH
- lidé MeSH
- mikro RNA genetika MeSH
- nádorová transformace buněk genetika MeSH
- nádory slinivky břišní diagnóza genetika MeSH
- rizikové faktory MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
- Názvy látek
- genetické markery MeSH
- mikro RNA MeSH
Pancreatic cancer is a disease with increasing incidence and high (and nearly unchanged) lethality that is caused mainly due to its late diagnosis. Risk factors for neoplastic transformation are especially chronic pancreatitis, diabetes mellitus, but also obesity and smoking. The search for suitable early markers becomes a key element of research in this area. Such markers could be microRNAs, short single-stranded RNA molecules functioning as regulators of translation. This article serves as a review of contemporary evidence of microRNA in diabetes mellitus and pancreatic cancer.