Complete Sequences of IncU Plasmids Harboring Quinolone Resistance Genes qnrS2 and aac(6')-Ib-cr in Aeromonas spp. from Ornamental Fish
Language English Country United States Media electronic-print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
26525788
PubMed Central
PMC4704210
DOI
10.1128/aac.01773-15
PII: AAC.01773-15
Knihovny.cz E-resources
- MeSH
- Aeromonas drug effects genetics isolation & purification MeSH
- Anti-Bacterial Agents pharmacology MeSH
- Genes, Bacterial * MeSH
- Drug Resistance, Bacterial genetics MeSH
- Bacterial Proteins genetics metabolism MeSH
- Quinolones pharmacology MeSH
- Gram-Negative Bacterial Infections microbiology veterinary MeSH
- Microbial Sensitivity Tests MeSH
- Fish Diseases microbiology MeSH
- Open Reading Frames MeSH
- Plasmids chemistry metabolism MeSH
- Gene Expression Regulation, Bacterial * MeSH
- Fishes microbiology MeSH
- Sequence Analysis, DNA MeSH
- DNA Transposable Elements MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
- Bacterial Proteins MeSH
- Quinolones MeSH
- DNA Transposable Elements MeSH
The nucleotide sequences of three IncU plasmids from Aeromonas spp. isolated from ornamental fish are described. They had a typical IncU backbone for plasmid replication and maintenance functions, but conjugative transfer modules were disrupted. The gene qnrS2 was inserted into mpR as a mobile insertion cassette. Novel Tn3 family transposons carrying putative toxin-antitoxin and plasmid stability genes were identified. The study demonstrates high plasticity of IncU plasmids from aquatic environments.
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GENBANK
KT315926, KT315927, KT315928
