Congenital coronary artery anomalies: a bridge from embryology to anatomy and pathophysiology--a position statement of the development, anatomy, and pathology ESC Working Group
Jazyk angličtina Země Velká Británie, Anglie Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem, přehledy
Grantová podpora
RG/12/15/29935
British Heart Foundation - United Kingdom
PubMed
26811390
DOI
10.1093/cvr/cvv251
PII: cvv251
Knihovny.cz E-zdroje
- Klíčová slova
- Anatomy, Congenital heart disease, Coronary arteries, Embryology, Pathology,
- MeSH
- anomálie koronárních cév * embryologie patologie patofyziologie MeSH
- ischemická choroba srdeční komplikace patologie MeSH
- kardiologie metody MeSH
- koronární cévy * anatomie a histologie růst a vývoj patologie MeSH
- lidé MeSH
- nemoci koronárních tepen vrozené patologie MeSH
- srdce anatomie a histologie fyziologie MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
Congenital coronary artery anomalies are of major significance in clinical cardiology and cardiac surgery due to their association with myocardial ischaemia and sudden death. Such anomalies are detectable by imaging modalities and, according to various definitions, their prevalence ranges from 0.21 to 5.79%. This consensus document from the Development, Anatomy and Pathology Working Group of the European Society of Cardiology aims to provide: (i) a definition of normality that refers to essential anatomical and embryological features of coronary vessels, based on the integrated analysis of studies of normal and abnormal coronary embryogenesis and pathophysiology; (ii) an animal model-based systematic survey of the molecular and cellular mechanisms that regulate coronary blood vessel development; (iii) an organization of the wide spectrum of coronary artery anomalies, according to a comprehensive anatomical and embryological classification scheme; (iv) current knowledge of the pathophysiological mechanisms underlying symptoms and signs of coronary artery anomalies, with diagnostic and therapeutic implications. This document identifies the mosaic-like embryonic development of the coronary vascular system, as coronary cell types differentiate from multiple cell sources through an intricate network of molecular signals and haemodynamic cues, as the necessary framework for understanding the complex spectrum of coronary artery anomalies observed in human patients.
Aix Marseille Université CNRS IBDM UMR 7288 Marseille France
Departamento de Biología Animal Instituto de Investigación Biomédica de Málaga Spain
Department of Cardiac Thoracic and Vascular Sciences University of Padua Padova Italy
Department of Cardiovascular Pathology St Georges's University of London London UK
Department of Experimental Biology Universidad de Jaén Jaén Spain
Experimental and Clinical Research Center Max Planck Institut for Clinical Genetics Berlin Germany
Institute of Genetic Medicine Newcastle University Centre for Life Newcastle upon Tyne UK
Marie Lannelongue Hospital M3C Paris Sud University Le Plessis Robinson France
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