Comparison of GreenLight laser and transurethral resection of the prostate baseline characteristics and outcomes: lessons learned from the Clinical Research Office of the Endourological Society GreenLight Laser Study
Jazyk angličtina Země Itálie Médium print-electronic
Typ dokumentu srovnávací studie, časopisecké články, multicentrická studie, pozorovací studie
PubMed
27706124
DOI
10.23736/s0393-2249.16.02721-1
PII: R19Y9999N00A16100502
Knihovny.cz E-zdroje
- MeSH
- hyperplazie prostaty chirurgie MeSH
- inkontinence moči etiologie MeSH
- laserová terapie přístrojové vybavení metody MeSH
- lidé MeSH
- prospektivní studie MeSH
- senioři MeSH
- transuretrální resekce prostaty přístrojové vybavení metody MeSH
- výsledek terapie MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
- pozorovací studie MeSH
- srovnávací studie MeSH
BACKGROUND: To compare baseline characteristics and outcomes of patients undergoing GreenLight laser vaporization (GL) or transurethral resection of the prostate (TURP) in a real life setting. METHODS: In this prospective observational cohort, the Clinical Research Office of the Endourological Society (CROES) collected data of consecutive GL or TURP treated patients. Treatment involved one of three GL laser powers (80 W, 120 W or 180 W) based on availability in each participating centre, or TURP. Data on baseline characteristics as well as functional measures were collected at three time points: 6-12 weeks, 6, and 12months after surgery. Functional measures included urinary flow parameters, perceived prostate function (IPSS), perceived erectile function (IIEF-5) and complications. RESULTS: Seven hundred thirteen patients underwent GL, and 234 patients underwent TURP. Overall, patients treated with GL show higher BMI, IIEF and medication use, together with lower urinary function (voided volume, incontinence, urinary retention) at baseline. After the procedure, despite higher antibiotic and antimuscarinic use and shorter hospital stay, readmission rates, PVR, PSA were higher, but Qmax, and IIEF were lower in the GL group. The rate of post-operative complications was 10.3% and 5.2% for the TURP and GL group, respectively (P=0.006). CONCLUSIONS: We were unable to categorically state which procedure is superior. This observational study confirms that treatment decision for either TURP or GL is not based on patient characteristics.
Department of Urology Advanced Urologic Surgery Institute Madrid Spain
Department of Urology AMC University Hospital Amsterdam The Netherlands
Department of Urology Asklepios Klinik St Georg Hamburg Germany
Department of Urology Center of Urology Buenos Aires Argentina
Department of Urology Faculty and Teaching Hospital Kralovske Vinohrady Prague Czech Republic
Department of Urology Hospital General Royo Villanova Zaragoza Spain
Department of Urology Isala Clinic Zwolle The Netherlands
Department of Urology King's College Hospital London UK
Department of Urology Private Lokman Hekim Hospitals Etlik Ankara Turkey
Department of Urology University of Oklahoma Health Sciences Center Oklahoma City Oklahoma OK USA
Department of Urology Urology of Virginia Eastern Virginia Medical School Virginia Beach VA USA
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