Department of Pediatrics General Faculty Hospital Prague 1st Faculty of Medicine Charles University and General University Hospital Prague Ke Karlovu 2 128 08 Prague Czech Republic

Department of Pediatrics George Washington University School of Medicine and Health Sciences Washington D C USA

Department of Pharmacology and Physiology George Washington University School of Medicine and Health Sciences Washington D C USA

Division of Clinical Pharmacology Children's National Health System Washington D C USA

Division of Paediatric Pharmacology and Pharmacometrics University of Basel Children's Hospital Basel Switzerland

Institute of Pharmacology 1st Faculty of Medicine Charles University and General University Hospital Prague Albertov 4 128 00 Prague 2 Czech Republic

Intensive Care and Department of Pediatric Surgery Erasmus MC Sophia Children's Hospital Rotterdam The Netherlands

Intensive Care Erasmus MC Sophia Children's Hospital Rotterdam The Netherlands

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