Inactivation of dermatophyte infection by nonthermal plasma on animal model
Language English Country Great Britain, England Media print
Document type Journal Article
PubMed
28339534
DOI
10.1093/mmy/myw094
PII: 2629000
Knihovny.cz E-resources
- Keywords
- Trichophyton, cometary discharge, dermatophytosis, guinea pig, skin mycosis,
- MeSH
- Antifungal Agents therapeutic use MeSH
- Administration, Topical MeSH
- Dermatomycoses therapy MeSH
- Disease Models, Animal MeSH
- Guinea Pigs MeSH
- Plasma Gases therapeutic use MeSH
- Trichophyton drug effects MeSH
- Treatment Outcome MeSH
- Animals MeSH
- Check Tag
- Guinea Pigs MeSH
- Male MeSH
- Female MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Antifungal Agents MeSH
- Plasma Gases MeSH
Superficial fungal infections are a major epidemiological issue with increasing prevalence and are a common global problem. This article describes experimental therapy of superficial fungal skin infection using low-temperature plasma. Groups of guinea pigs were artificially infected with Trichophyton mentagrophytes SK 3286 dermatophyte and treated with plasma produced by a DC cometary discharge with an inserted grid. The course of infection was a week shorter and milder in animals treated by plasma than that in nontreated animals, the significant lowering of dermatophytic germs also occurred in the treated group. The exposure to plasma causes no harm to experimental animals. The results allow for the development of a new dermatophytoses therapy by low temperature plasma treatment.
References provided by Crossref.org
Inactivation of Dermatophytes Causing Onychomycosis and Its Therapy Using Non-Thermal Plasma