A prospective international Aspergillus terreus survey: an EFISG, ISHAM and ECMM joint study
Language English Country England, Great Britain Media print-electronic
Document type Journal Article, Multicenter Study
PubMed
28412383
DOI
10.1016/j.cmi.2017.04.012
PII: S1198-743X(17)30220-3
Knihovny.cz E-resources
- Keywords
- Amphotericin B, Aspergillosis, Aspergillus terreus, Crytic species, In vitrosusceptibility,
- MeSH
- Amphotericin B pharmacology MeSH
- Antifungal Agents pharmacology MeSH
- Aspergillus classification drug effects isolation & purification MeSH
- Aspergillosis epidemiology microbiology MeSH
- Epidemiological Monitoring MeSH
- Humans MeSH
- Microbial Sensitivity Tests MeSH
- Prevalence MeSH
- Prospective Studies MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Multicenter Study MeSH
- Geographicals
- Europe epidemiology MeSH
- Names of Substances
- Amphotericin B MeSH
- Antifungal Agents MeSH
OBJECTIVES: A prospective international multicentre surveillance study was conducted to investigate the prevalence and amphotericin B susceptibility of Aspergillus terreus species complex infections. METHODS: A total of 370 cases from 21 countries were evaluated. RESULTS: The overall prevalence of A. terreus species complex among the investigated patients with mould-positive cultures was 5.2% (370/7116). Amphotericin B MICs ranged from 0.125 to 32 mg/L, (median 8 mg/L). CONCLUSIONS: Aspergillus terreus species complex infections cause a wide spectrum of aspergillosis and the majority of cryptic species display high amphotericin B MICs.
A O U Policlinico Vittorio Emanuele Catania Biometec University of Catania Italy
CBS KNAW Fungal Biodiversity Centre Utrecht The Netherlands
Clinical Microbiology Puerta del Mar University Hospital University of Cádiz Cádiz Spain
Department 1 for Internal Medicine University Hospital of Cologne Cologne Germany
Department of Biomedical and Biotechnological Sciences University of Catania Catania Italy
Department of Biomedical Sciences for Health Università degli Studi di Milano Milan Italy
Department of Dermatology Hospital Ernest Lluch Martin Calatayud Zaragoza Spain
Department of Hygiene and Medical Microbiology Klinikum Wels Grieskirchen Wels Austria
Department of Medical Microbiology Hacettepe University Medical School Ankara Turkey
Department of Medical Mycology Vallabhbhai Patel Chest Institute University of Delhi Delhi India
Department of Microbiology and Immunology KU Leuven Leuven Belgium
Department of Public Health and Pediatrics Microbiology Division Turin Italy
Division of Hygiene and Medical Microbiology Medical University of Innsbruck Innsbruck Austria
Division of Mycology Department of Medial Microbiology Chandigarh India
Escola Paulista de Medicina Federal University of São Paulo São Paulo Brazil
Institute for Medical Microbiology Immunology and Hygiene University of Cologne Cologne Germany
Institute of Hygiene Microbiology and Environmental Medicine Medical University of Graz Graz Austria
Microbiologia Hospital Universitario Miguel Servet IIS Aragon Universidad de Zaragoza Zaragoza Spain
Microbiology Institute ASST Papa Giovanni XXIII Bergamo Italy
Mycology Reference Laboratory Public Health England Bristol UK
National Centre for Microbiology Instituto de Salud Carlos 3 Madrid Spain
School of Medicine European University Cyprus Nicosia Cyprus
Servei de Microbiologia Hospital de la Santa Creu 1 Sant Pau Barcelona Spain
The University of Texas MD Anderson Cancer Center Houston TX USA
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