Glioblastoma Multiforme, Diagnosis and Treatment; Recent Literature Review
Jazyk angličtina Země Spojené arabské emiráty Médium print
Typ dokumentu časopisecké články, přehledy
PubMed
28521700
DOI
10.2174/0929867324666170516123206
PII: CMC-EPUB-83465
Knihovny.cz E-zdroje
- Klíčová slova
- Biologic agent, chemotherapy, glioblastoma multiforme, immunotherapy, radiation therapy, vaccination.,
- MeSH
- antitumorózní látky alkylující terapeutické užití MeSH
- buněčná a tkáňová terapie MeSH
- dendritické buňky imunologie metabolismus MeSH
- glioblastom diagnóza mortalita terapie MeSH
- imunoterapie MeSH
- kombinovaná terapie MeSH
- lidé MeSH
- monoklonální protilátky terapeutické užití MeSH
- nádory mozku diagnóza mortalita terapie MeSH
- Poliovirus genetika imunologie metabolismus MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
- Názvy látek
- antitumorózní látky alkylující MeSH
- monoklonální protilátky MeSH
BACKGROUND: Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor, with an incidence of 3.19 cases per 100,000 person years and remarkably poor prognosis showing a 5-year survival rate of 4-5%, and only a 26-33% survival rate at 2 years in clinical trials. OBJECTIVE: In this paper, we review the different types of treatment modalities based on the relevant databases. Methods of diagnosis will be described briefly. METHOD: Systemic compilation of the relevant literature. RESULTS & CONCLUSION: Today's treatments cannot cure GBM patients but only extend their overall survival. The use of chemoradiation, immunotherapy, and radio sensitizers as an adjuvant therapy cannot reduce the high rates of recurrence within a few months after treatment. Radiotherapy will remain the backbone of the treatment but new treatment modalities must be developed.
Bad Trissl Clinic Department of Oncology Oberaudorf Germany
Barzilai Medical Center Department of Oncology Ashkelon Israel
Barzilai Medical Center Department of Orthopedic Surgery Ashkelon Israel
Faculty of Medicine Charles University Prague Czech Republic
Citace poskytuje Crossref.org
