Our experience in the treatment of idiopathic sensorineural hearing loss (ISNHL): Effect of combination therapy with HBO₂ and vasodilator infusion therapy
Language English Country United States Media print
Document type Comparative Study, Journal Article
PubMed
28777514
Knihovny.cz E-resources
- Keywords
- hyperbaric oxygen therapy, idiopathic sensorineural hearing loss, vasodilator infusion,
- MeSH
- Analysis of Variance MeSH
- Audiometry MeSH
- Adult MeSH
- Hyperbaric Oxygenation methods MeSH
- Combined Modality Therapy methods MeSH
- Middle Aged MeSH
- Humans MeSH
- Hearing Loss, Sudden therapy MeSH
- Statistics, Nonparametric MeSH
- Hearing Loss, Sensorineural therapy MeSH
- Retrospective Studies MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Hearing physiology MeSH
- Tinnitus therapy MeSH
- Vasodilator Agents therapeutic use MeSH
- Age Factors MeSH
- Treatment Outcome MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Comparative Study MeSH
- Names of Substances
- Vasodilator Agents MeSH
Idiopathic sensorineural hearing loss (ISNHL) is a hearing impairment that occurs suddenly with onset over a period of 24 to 72 hours, affecting at least three adjacent frequencies with hearing loss of 30 decibels or more, caused by damage to the inner ear or auditory nerve without clear reasons. The treatment of ISNHL is still a hot topic. In a retrospective study, we examined 88 patients with ISNHL (2008-2013). The objective of the study was to compare the effects of two different types of therapy: vasodilator infusion treatment combined with hyperbaric oxygen (HBO₂) therapy vs. vasodilator infusion therapy alone. We investigated the correlation between the type of audiometric curve and hearing gain after treatment, the correlation between the age and the effectiveness of treatment, plus the effect of therapy on tinnitus. We found a statistically significant (p⟨0.0001) therapeutic effect in both treatment modalities: 55% with HBO₂ therapy vs. 65% without HBO₂. The difference between the two methods is not statistically significant. The best effect of treatment was observed in patients with apicocochlear hearing impairment. The age of patients in our group had no statistically significant relevance. Alleviation of tinnitus was observed mainly in patients with apicocochlear type of hearing loss.