In the last decade, the control of avian influenza virus has experienced many difficulties, which have caused major global agricultural problems that have also led to public health consequences. Conventional biochemical methods are not sufficient to detect and control agricultural pathogens in the field due to the growing demand for food and subsidiary products; thus, studies aiming to develop potent alternatives to conventional biochemical methods are urgently needed. In this review, emerging detection systems, their applicability to diagnostics, and their therapeutic possibilities in view of nanotechnology are discussed. Nanotechnology-based sensors are used for rapid, sensitive and cost-effective diagnostics of agricultural pathogens. The application of different nanomaterials promotes interactions between these materials and the virus, which enables researchers to construct portable electroanalytical biosensing analyser that should effectively detect the influenza virus. The present review will provide insights into the guidelines for future experiments to develop better techniques to detect and control influenza viruses.

Department of Chemistry and Biochemistry Mendel University in Brno Zemedelska 1 CZ 613 00 Brno Czech Republic; Central European Institute of Technology Brno University of Technology Technicka 3058 10 CZ 616 00 Brno Czech Republic

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Cattoli G., Fusaro A., Monne I., Coven F., Joannis T., El-Hamid H.S., Hussein A.A., Cornelius C., Amarin N.M., Mancin M., Holmes E.C., Capua I. Vaccine. 2011;29:9368–9375. PubMed

Leong H.K., Goh C.S., Chew S.T., Lim C.W., Lin Y.N., Chang S.F., Yap H.H., Bin Chua S. Ann. Acad. Med. Singap. 2008;37:504–509. PubMed

Bengis R.G., Leighton F.A., Fischer J.R., Artois M., Morner T., Tate C.M. Rev. Sci. Tech. 2004;23:497–511. PubMed

Jones B.A., Grace D., Kock R., Alonso S., Rushton J., Said M.Y., McKeever D., Mutua F., Young J., McDermott J., Pfeiffer D.U. Proc. Natl. Acad. Sci. U. S. A. 2013;110:8399–8404. PubMed PMC

Beaudoin A.L., Kitikoon P., Schreiner P.J., Singer R.S., Sasipreeyajan J., Amonsin A., Gramer M.R., Pakinsee S., Bender J.B. Transbound. Emerg. Dis. 2014;61:362–374. PubMed

Sakoda Y., Ito H., Uchida Y., Okamatsu M., Yamamoto N., Soda K., Nomura N., Kuribayashi S., Shichinohe S., Sunden Y., Umemura T., Usui T., Ozaki H., Yamaguchi T., Murase T., Ito T., Saito T., Takada A., Kida H. J. Gen. Virol. 2012;93:541–550. PubMed

Loth L., Gilbert M., Osmani M.G., Kalam A.M., Xiao X. Prev. Vet. Med. 2010;96:104–113. PubMed PMC

Wang C., Wang J., Su W., Gao S., Luo J., Zhang M., Xie L., Liu S., Liu X., Chen Y., Jia Y., Zhang H., Ding H., He H. J. Infect. Dis. 2014;209:34–37. PubMed

Wu X.X., Tian H.Y., Zhou S., Chen L.F., Xu B. Sci. China-Earth Sci. 2014;57:189–203. PubMed PMC

Falanga A., Vitiello M.T., Cantisani M., Tarallo R., Guarnieri D., Mignogna E., Netti P., Pedone C., Galdiero M., Galdiero S. Nanomed.-Nanotechnol. Biol. Med. 2011;7:925–934. PubMed

Cao C., Gontard L.C., Thuy Tram L.L., Wolff A., Bang D.D. Small. 2011;7:1701–1708. PubMed

Miranda O.R., Creran B., Rotello V.M. Curr. Opin. Chem. Biol. 2010;14:728–736. PubMed PMC

Heger Z., Cernei N., Gumulec J., Masarik M., Eckschlager T., Hrabec R., Zitka O., Adam V., Kizek R. Oncol. Rep. 2014;31:1846–1854. PubMed

Esposito S., Molteni C.G., Daleno C., Valzano A., Tagliabue C., Bosis S., Galeone C., Milani G., Principi N. J. Clin. Virol. 2009;46 S25–S25.

Westgeest K.B., Bestebroer T.M., Spronken M.I.J., Gao J., Couzens L., Osterhaus A., Eichelberger M., Fouchier R.A.M., de Graaf M. J. Virol. Methods. 2015;217:55–63. PubMed PMC

Qasim M., Lim D.J., Park H., Na D. J. Nanosci. Nanotechnol. 2014;14:7374–7387. PubMed

Esfandyarpour R., Esfandyarpour H., Harris J.S., Davis R.W. Nanotechnology. 2013;24:1–23. PubMed PMC

Sun W., Jiao K., Zhang S.S. Talanta. 2001;55:1211–1218. PubMed

Cella L.N., Chen W., Myung N.V., Mulchandani A. J. Am. Chem. Soc. 2010;132:5024–5026. PubMed PMC

Lung O., Beeston A., Ohene-Adjei S., Pasick J., Hodko D., Hughes K.B., Furukawa-Stoffer T., Fisher M., Deregt D. J. Virol. Methods. 2012;185:244–253. PubMed

Charlton B., Crossley B., Hietala S. Comp. Immunol. Microbiol. Infect. Dis. 2009;32:341–350. PubMed

Watanabe Y., Ito T., Ibrahim M.S., Arai Y., Hotta K., Phuong H.V.M., Hang N.L.K., Mai L.Q., Soda K., Yamaoka M., Poetranto E.D., Wulandari L., Hiramatsu H., Daidoji T., Kubota-Koketsu R., Sriwilaijaroen N., Nakaya T., Okuno Y., Takahashi T., Suzuki T., Hotta H., Yamashiro T., Hayashi T., Morita K., Ikuta K., Suzuki Y. Biosens. Bioelectron. 2015;65:211–219. PubMed PMC

Chen H., Ou Q.B., Tang Y., Gao X.H., Wu L.L., Xue C., Yu C.M., Cui J.T., Diao Y.X. PLoS One. 2014;9:1–6. PubMed PMC

Li J.F., Zou M.Q., Chen Y., Xue Q., Zhang F., Li B.B., Wang Y.F., Qi X.H., Yang Y. Anal. Chim. Acta. 2013;782:54–58. PubMed

Comin A., Toft N., Stegeman A., Klinkenberg D., Marangon S. Influenza Other Respir. Viruses. 2013;7:257–264. PubMed PMC

Zhang R.Q., Liu S.L., Zhao W., Zhang W.P., Yu X., Li Y., Li A.J., Pang D.W., Zhang Z.L. Anal. Chem. 2013;85:2645–2651. PubMed

Kang X.P., Wu W.L., Zhang C.T., Liu L.C., Feng H.H., Xu L.Z., Zheng X., Yang H.L., Jiang Y.Q., Xu B.L., Xu J., Yang Y.H., Chen W.J. J. Virol. Methods. 2014;206:140–143. PubMed

Fan J., Cui D., Lau S.Y., Xie G.L., Guo X.C., Zheng S.F., Huang X.F., Yang S.G., Yang X.Z., Huo Z.X., Yu F., Lou J.Z., Tian L., Li X.F., Dong Y.J., Zhu Q.Y., Chen Y. BMC Infect. Dis. 2014;14:1–9. PubMed PMC

Zhu L., Zhu C.C., Deng G.Q., Zhang L., Zhao S.M., Lin J.H., Li L., Jiao P.R., Liao M., Liu Y. Anal. Methods. 2014;6:2628–2632.

Rodrigo M.A.M., Zitka O., Krejcova L., Hynek D., Masarik M., Kynicky J., Heger Z., Adam V., Kizek R. Int. J. Electrochem. Sci. 2014;9:3431–3439.

Zhao Y.H., Wang X.R., Chen P.C., Zeng X.Y., Bao H.M., Wang Y.H., Xu X.L., Jiang Y.P., Chen H.L., Li G.X. J. Vet. Med. Sci. 2015;77:413–419. PubMed PMC

Heger Z., Zitka O., Fohlerova Z., Rodrigo M.A.M., Hubalek J., Kizek R., Adam V. Chem. Pap. 2015;69:54–61.

Hill R.T. Wiley Interdiscip. Rev.-Nanomed. Nanobiotechnol. 2015;7:152–168. PubMed PMC

Sanvicens N., Pastells C., Pascual N., Marco M.P. Trac-Trends Anal. Chem. 2009;28:1243–1252.

Joo K.-I., Tai A., Wang P. Wiley-VCH Verlag GmbH & Co; 2007. Imaging and Tracking of Viruses Using Quantum Dots, Nanotechnologies for the Life Sciences; p. 425. KGaA.

Deng Z.T., Zhang Y., Yue J.C., Tang F.Q., Wei Q. J. Phys. Chem. B. 2007;111:12024–12031. PubMed

Wei X.F., Zheng L.Y., Luo F., Lin Z.Y., Guo L.H., Qiu B., Chen G.N. J. Mat. Chem. B. 2013;1:1812–1817. PubMed

Brockman L., Wang R., Lum J., Li Y. Open J. app. Biosens. 2013;2:97–103.

Shojaei T.R., Tabatabaei M., Shawky S., Salleh M.A.M., Bald D. Mol. Biol. Rep. 2015;42:187–199. PubMed

Grabowska I., Malecka K., Jarocka U., Radecki J., Radecka H. Acta Biochim. Pol. 2014;61:471–478. PubMed

Krejcova L., Hynek D., Adam V., Hubalek J., Kizek R. Int. J. Electrochem. Sci. 2012;7:10779–10801.

Ryvolova M., Chomoucka J., Drbohlavova J., Kopel P., Babula P., Hynek D., Adam V., Eckschlager T., Hubalek J., Stiborova M., Kaiser J., Kizek R. Sensors. 2012;12:14792–14820. PubMed PMC

Diba F.S., Kim S., Lee H.J. Biosens. Bioelectron. 2015;72:355–361. PubMed

Cha M.S., Lee J.K., Cho S.H., Park J.G., Lee H.Y., Lim S.H., Yoon Y.R. J. Nanosci. Nanotechnol. 2013;13:5245–5249. PubMed

Medina-Sanchez M., Ibarlucea B., Perez N., Karnaushenko D.D., Weiz S.M., Baraban L., Cuniberti G., Schmidt O.G. Nano Lett. 2016;16:4288–4296. PubMed

Chen L.Y., Neethirajan S. Sensors. 2015;15:8852–8865. PubMed PMC

Nguyen T.H., Ung T.D.T., Vu T.H., Tran T.K.C., Dong V.Q., Dinh D.K., Nguyen Q.L. Adv. Nat. Sci. Nanosci. Nanotech. 2012;3:1–5.

Chen L.P., Sheng Z.H., Zhang A.D., Guo X.B., Li J.K., Han H.Y., Jin M.L. Luminescence. 2010;25:419–423. PubMed

Zhang Y., Deng Z.T., Yue J.C., Tang F.Q., Wei Q. Anal. Biochem. 2007;364:122–127. PubMed

Krejcova L., Nejdl L., Rodrigo M.A.M., Zurek M., Matousek M., Hynek D., Zitka O., Kopel P., Adam V., Kizek R. Biosens. Bioelectron. 2014;54:421–427. PubMed

Koole R., Mulder W.J.M., van Schooneveld M.M., Strijkers G.J., Meijerink A., Nicolay K. Wiley Interdiscip. Rev.-Nanomed. Nanobiotechnol. 2009;1:475–491. PubMed

Cao D., Li C.Y., Kang Y.F., Lin Y., Cui R., Pang D.W., Tang H.W. Biosens. Bioelectron. 2016;86:1031–1037. PubMed

Zhang H.F., Ma X.M., Hu S.S., Lin Y., Guo L.H., Qiu B., Lin Z.Y., Chen G.N. Biosens. Bioelectron. 2016;79:874–880. PubMed

Fan H., Ju P., Ai S.Y. Sens. Actuator B-Chem. 2010;149:98–104.

Krejcova L., Hynek D., Kopel P., Adam V., Hubalek J., Trnkova L., Kizek R. Chromatographia. 2013;76:355–362.

Wang X., Lou X.H., Wang Y., Guo Q.C., Fang Z., Zhong X.H., Mao H.J., Jin Q.H., Wu L., Zhao H., Zhao J.L. Biosens. Bioelectron. 2010;25:1934–1940. PubMed

Xu L.Z., Wang R.H., Kelso L.C., Ying Y.B., Li Y.B. Sens. Actuator B-Chem. 2016;234:98–108.

Wang J.H., Lu P., Yan J.N., Zhang Y.F., Huang L.Y., Ali Z.S., Liu B., Li Z.Y., He N.Y. J. Biomed. Nanotechnol. 2016;12:710–716. PubMed

Zhou C.H., Shu Y., Hong Z.Y., Pang D.W., Zhang Z.L. Chem.-Asian J. 2013;8:2220–2226. PubMed

Zhao W., Zhang W.P., Zhang Z.L., He R.L., Lin Y., Xie M., Wang H.Z., Pang D.W. Anal. Chem. 2012;84:2358–2365. PubMed

Zou X., Huang H., Gao Y., Su X.G. Analyst. 2012;137:648–653. PubMed

Li D.J., Wang J.P., Wang R.H., Li Y.B., Abi-Ghanem D., Berghman L., Hargis B., Lu H.G. Biosens. Bioelectron. 2011;26:4146–4154. PubMed

Lum J., Wang R.H., Lassiter K., Srinivasan B., Abi-Ghanem D., Berghman L., Hargis B., Tung S., Lu H.G., Li Y.B. Biosens. Bioelectron. 2012;38:67–73. PubMed

Fu Y.C., Callaway Z., Lum J., Wang R.H., Lin J.H., Li Y.B. Anal. Chem. 2014;86:1965–1971. PubMed

Wang R.H., Lin J.H., Lassiter K., Srinivasan B., Lin L., Lu H.G., Tung S., Hargis B., Bottje W., Berghman L., Li Y.B. J. Virol. Methods. 2011;178:52–58. PubMed

Zhou C.H., Wu Z., Chen J.J., Xiong C.C., Chen Z., Pang D.W., Zhang Z.L. Chem.-Asian J. 2015;10:1387–1393. PubMed

Heger Z., Cernei N., Guran R., Michalek P., Milosavljevic V., Kopel P., Zitka O., Kynicky J., Lany P., Adam V., Kizek R. Int. J. Electrochem. Sci. 2014;9:3374–3385.

Nguyen V.T., Seo H.B., Kim B.C., Kim S.K., Song C.S., Gu M.B. Biosens. Bioelectron. 2016;86:293–300. PubMed

Karash S., Wang R.H., Kelso L., Lu H.G., Huang T.J., Li Y.B. J. Virol. Methods. 2016;236:147–156. PubMed

Jarocka U., Sawicka R., Gora-Sochacka A., Sirko A., Dehaen W., Radecki J., Radecka H. Sens. Actuator B-Chem. 2016;228:25–30.

Jarocka U., Sawicka R., Gora-Sochacka A., Sirko A., Zagorski-Ostoja W., Radecki J., Radecka H. Sensors. 2014;14:15714–15728. PubMed PMC

Kim Y.T., Jung J.H., Choi Y.K., Seo T.S. Biosens. Bioelectron. 2014;61:485–490. PubMed

Ye W.W., Tsang M.K., Liu X., Yang M., Hao J.H. Small. 2014;10:2390–2397. PubMed

Wei J.H., Zheng L.T., Lv X., Bi Y.H., Chen W.W., Zhang W., Shi Y., Zhao L., Sun X.M., Wang F., Cheng S.H., Yan J.H., Liu W.J., Jiang X.Y., Gao G.F., Li X.B. ACS Nano. 2014;8:4600–4607. PubMed

Zhou C.H., Zhao J.Y., Pang D.W., Zhang Z.L. Anal. Chem. 2014;86:2752–2759. PubMed

Liu Y.J., Zhang L.Q., Wei W., Zhao H.Y., Zhou Z.X., Zhang Y.J., Liu S.Q. Analyst. 2015;140:3989–3995. PubMed

Shi L., Chu Z.Y., Dong X.L., Jin W.Q., Dempsey E. Nanoscale. 2013;5:10219–10225. PubMed

Marin M.J., Rashid A., Rejzek M., Fairhurst S.A., Wharton S.A., Martin S.R., McCauley J.W., Wileman T., Field R.A., Russell D.A. Org. Biomol. Chem. 2013;11:7101–7107. PubMed

Zhao J.Q., Tang S.X., Storhoff J., Marla S., Bao Y.P., Wang X., Wong E.Y., Ragupathy V., Ye Z.P., Hewlett I.K. BMC Biotechnol. 2010;10:1–9. PubMed PMC

Park T.J., Lee S.J., Kim D.K., Heo N.S., Park J.Y., Lee S.Y. Talanta. 2012;89:246–252. PubMed

Emami T., Madani R., Rezayat S.M., Golchinfar F., Sarkar S. J. Appl. Poult. Res. 2012;21:563–566.

Wang R.H., Xu L.Z., Li Y.B. Biosens. Bioelectron. 2015;67:400–407. PubMed

Li Y.X., Hong M., Qiu B., Lin Z.Y., Chen Y.T., Cai Z.W., Chen G.N. Biosens. Bioelectron. 2014;54:358–364. PubMed

Huang J.L., Xie Z.X., Xie Z.Q., Luo S.S., Xie L.J., Huang L., Fan Q., Zhang Y.F., Wang S., Zeng T.T. Anal. Chim. Acta. 2016;913:121–127. PubMed

Jazayeri S.D., Ideris A., Shameli K., Moeini H., Omar A.R. Int. J. Nanomed. 2013;8:781–790. PubMed PMC

Yang Z.H., Zhuo Y., Yuan R., Chai Y.Q. Biosens. Bioelectron. 2015;69:321–327. PubMed

Xie Z.X., Huang J.L., Luo S.S., Xie Z.Q., Xie L.J., Liu J.B., Pang Y.S., Deng X.W., Fan Q. PLoS One. 2014;9:1–8. PubMed PMC

Low S.S., Tan M.T.T., Loh H.S., Khiew P.S., Chiu W.S. Anal. Chim. Acta. 2016;903:131–141. PubMed

Liu X.G., Cheng Z.Q., Fan H., Ai S.Y., Han R.X. Electrochim. Acta. 2011;56:6266–6270.

Gao A.R., Lu N., Dai P.F., Li T., Pei H., Gao X.L., Gong Y.B., Wang Y.L., Fan C.H. Nano Lett. 2011;11:3974–3978. PubMed

Fang L.X., Cao J.T., Huang K.J. J. Electroanal. Chem. 2015;746:1–8.

Yeo S.J., Huong D.T., Hong N.N., Li C.Y., Choi K., Yu K., Choi D.Y., Chong C.K., Choi H.S., Mallik S.K., Kim H.S., Sung H.W., Park H. Theranostics. 2014;4:1239–1249. PubMed PMC

Ross K.A., Loyd H., Wu W.W., Huntimer L., Wannemuehler M.J., Carpenter S., Narasimhan B. J. Biomed. Mater. Res. Part A. 2014;102:4161–4168. PubMed

Moon H.J., Lee J.S., Talactac M.R., Chowdhury M.Y.E., Kim J.H., Park M.E., Choi Y.K., Sung M.H., Kim C.J. Vet. Microbiol. 2012;160:277–289. PubMed

Wu Z., Zhou C.H., Chen J.J., Xiong C.C., Chen Z., Pang D.W., Zhang Z.L. Biosens. Bioelectron. 2015;68:586–592. PubMed

Yang S.Y., Chieh J.J., Wang W.C., Yu C.Y., Lan C.B., Chen J.H., Horng H.E., Hong C.Y., Yang H.C., Huang W. J. Virol. Methods. 2008;153:250–252. PubMed

Lim S.H., Bestvater F., Buchy P., Mardy S., Yu A.D.C. Sensors. 2009;9:5590–5599. PubMed PMC

Mu B., Huang X.L., Bu P.C., Zhuang J., Cheng Z.X., Feng J., Yang D.L., Dong C.S., Zhang J.B., Yan X.Y. J. Virol. Methods. 2010;169:282–289. PubMed

Kamikawa T.L., Mikolajczyk M.G., Kennedy M., Zhong L.L., Zhang P., Setterington E.B., Scott D.E., Alocilja E.C. IEEE Trans. Nanotechnol. 2012;11:88–96. PubMed PMC

Zhang B.H., Wang R.H., Wang Y.X., Li Y.B. 2013 IEEE Sensors, Ieee; New York: 2013. Ieee, a Portable Impedance Biosensor for Detection of Multiple Avian Influenza Viruses; pp. 337–340.

Han J.H., Lee D.Y., Chew C.H.C., Kim T., Pak J.J.H. Sens. Actuator B-Chem. 2016;228:36–42.

Sun Y., Xu L., Zhang F.D., Song Z.G., Hu Y.W., Ji Y.J., Shen J.Y., Li B., Lu H.Z., Yang H.F. Biosens. Bioelectron. 2017;89:906–912. PubMed

Peiris J.S.M., de Jong M.D., Guan Y. Clin. Microbiol. Rev. 2007;20:243–267. PubMed PMC

Kiss I., German P., Sami L., Antal M., Farkas T., Kardos G., Kecskemeti S., Dan A., Belak S. Acta Vet. hung. 2006;54:525–533. PubMed

Gustafsdottir S.M., Nordengrahn A., Fredriksson S., Wallgren P., Rivera E., Schallmeiner E., Merza M., Landegren U. Clin. Chem. 2006;52:1152–1160. PubMed

Dugan V.G., Dunham E.J., Jin G., Sheng Z.M., Kaser E., Nolting J.M., Alexander H.L., Jr., Slemons R.D., Taubenberger J.K. Virology. 2011;417:98–105. PubMed PMC

Kraus R.H., Kerstens H.H., Van Hooft P., Crooijmans R.P., Van Der Poel J.J., Elmberg J., Vignal A., Huang Y., Li N., Prins H.H., Groenen M.A. BMC Genomics. 2011;12:1–11. PubMed PMC

Leon A.J., Banner D., Xu L., Ran L., Peng Z., Yi K., Chen C., Xu F., Huang J., Zhao Z., Lin Z., Huang S.H., Fang Y., Kelvin A.A., Ross T.M., Farooqui A., Kelvin D.J. J. Virol. 2013;87:1957–1966. PubMed PMC

Van Reeth K. Vet. Res. 2007;38:243–260. PubMed

Mueller K.H., Kakkola L., Nagaraj A.S., Cheltsov A.V., Anastasina M., Kainov D.E. Trends Pharmacol. Sci. 2012;33:89–99. PubMed

Petryayeva E., Algar W.R., Medintz I.L. Appl. Spectrosc. 2013;67:215–252. PubMed

Giljohann D.A., Seferos D.S., Daniel W.L., Massich M.D., Patel P.C., Mirkin C.A. Angew. Chem.-Int. Ed. 2010;49:3280–3294. PubMed PMC