Vector Control and Insecticidal Resistance in the African Malaria Mosquito Anopheles gambiae
Language English Country United States Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
- MeSH
- Acetylcholinesterase chemistry metabolism MeSH
- Anopheles parasitology MeSH
- Insecticides chemistry pharmacology MeSH
- Mosquito Vectors drug effects MeSH
- Humans MeSH
- Malaria parasitology pathology MeSH
- Drug Design MeSH
- Insecticide Resistance * MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Acetylcholinesterase MeSH
- Insecticides MeSH
Mosquito-borne diseases (including malaria) belong among the leading causes of death in humans. Vector control is a crucial part of the global strategy for management of mosquito-associated diseases, when insecticide use is the most important component in this effort. However, drug and insecticide resistance threaten the successes made with existing methods. Reduction or elimination of malaria is not possible without effective mosquito control. This article reviews current strategies of intervention in vector control to decrease transmission of disease and covers current relevant knowledge in molecular biology, biochemistry, and medicinal chemistry.
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