A metabolic switch in proteasome inhibitor-resistant multiple myeloma ensures higher mitochondrial metabolism, protein folding and sphingomyelin synthesis
Jazyk angličtina Země Itálie Médium print-electronic
Typ dokumentu dopisy, práce podpořená grantem
PubMed
30792209
PubMed Central
PMC6717569
DOI
10.3324/haematol.2018.207704
PII: haematol.2018.207704
Knihovny.cz E-zdroje
- MeSH
- bortezomib farmakologie MeSH
- chemorezistence * MeSH
- homeostáza MeSH
- inhibitory proteasomu farmakologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- lipidy chemie MeSH
- metabolomika MeSH
- mitochondrie metabolismus MeSH
- mnohočetný myelom farmakoterapie MeSH
- nádorové buněčné linie MeSH
- oligopeptidy farmakologie MeSH
- peroxid vodíku chemie MeSH
- proteasomový endopeptidasový komplex metabolismus MeSH
- protinádorové látky farmakologie MeSH
- protokoly protinádorové kombinované chemoterapie farmakologie MeSH
- reaktivní formy kyslíku metabolismus MeSH
- regulace genové exprese u nádorů MeSH
- sbalování proteinů MeSH
- senioři MeSH
- sfingomyeliny biosyntéza MeSH
- stanovení celkové genové exprese MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- dopisy MeSH
- práce podpořená grantem MeSH
- Názvy látek
- bortezomib MeSH
- carfilzomib MeSH Prohlížeč
- inhibitory proteasomu MeSH
- lipidy MeSH
- oligopeptidy MeSH
- peroxid vodíku MeSH
- proteasomový endopeptidasový komplex MeSH
- protinádorové látky MeSH
- reaktivní formy kyslíku MeSH
- sfingomyeliny MeSH
Department of Chemistry University of Florida Gainesville FL USA
Department of Histology and Embryology Faculty of Medicine Masaryk University Brno Czech Republic
Department of Pharmacology and Therapeutics University of Florida Gainesville FL USA
UF Health Cancer Center University of Florida Gainesville FL USA
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