Nowadays, the interest in manufacturing non-alcoholic or low alcoholic content beverages from alcoholic beverages is a current challenge for food technologists; this is due to the fact that huge consumption of alcoholic beverages may produce health problems in the costumers. In principle, the post-fermentation ethanol removal from alcoholic beverages is carried out by means of evaporation or distillation. Such current dealcoholization methodologies are efficiently removing the ethanol, however, some organoleptic compounds can also be lost during the process. This makes the dealcoholization process highly sensitive in order to preserve the quality properties of the beverages. Thereby, membrane-based technologies, which use perm-selective barriers for the separation, have been highly promoted for such purpose. Pervaporation (PV) technology is indeed one of these technologies aimed for ethanol removal. Herein, the goal of this review is to provide a compelling overview of the most relevant findings for the production of non-alcoholic beverages (such as beer and wine) by means of PV. Particular attention is paid to experimental results which provide compelling feedback about the accurate ethanol removal and minimal changes on physicochemical properties of the beverages. Moreover, some theoretical basis of such technology, as well as key criteria for a more efficient dealcoholization, are also given.

University of Chemistry and Technology Prague Technická 5 166 28 Prague 6 Czech Republic

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Afonso C, Crespo J, Anastas P (2015) Green separation processes: fundamentals and applications, 1st edn. Wiley, Weinheim, pp 1–383

Andrés-Iglesias C, García-Serna J, Montero O, Blanco CA. Simulation and flavor compound analysis of dealcoholized beer via one-step vacuum distillation. Food Res Int. 2015;76:751–760. PubMed

Andrés-Iglesias C, Blanco CA, García-Serna J, Pando V, Montero O. Volatile compound profiling in commercial lager regular beers and derived alcohol-free beers after dealcoholization by vacuum distillation. Food Anal Methods. 2016;9(11):3230–3241.

Baker RW, Wijmans JG, Huang Y. Permeability, permeance and selectivity: a preferred way of reporting pervaporation performance data. J Membr Sci. 2010;348(1–2):346–352.

Bartolomé B, Peña-Neira A, Gómez-Cordovés C. Phenolics and related substances in alcohol-free beers. Eur Food Res Technol. 2000;210(6):419–423.

Belisario-Sánchez YY, Taboada-Rodríguez A, Marín-Iniesta F, Iguaz-Gainza A, López-Gómez A. Aroma recovery in wine dealcoholization by SCC distillation. Food Bioprocess Technol. 2012;5(6):2529–2539.

Blanco CA, Andrés-Iglesias C, Montero O. Low-alcohol beers: flavor compounds, defects, and improvement strategies. Crit Rev Food Sci Nutr. 2016;56(8):1379–1388. PubMed

Brányik T, Silva DP, Baszczyňski M, Lehnert R, Almeida E. A review of methods of low alcohol and alcohol-free beer production. J Food Eng. 2012;108(4):493–506.

Brazinha C, Crespo JG. Valorization of food processing streams for obtaining extracts enriched in biologically active compounds. In: Cassano A, Drioli E, editors. Integrated membrane operations in the food production. 1. Berlin: Degruyter; 2014. pp. 295–310.

Cartron E, Fouret G, Carbonneau MA, Lauret C, Michel F, Monnier L, et al. Red-wine beneficial long-term effect on lipids but not on antioxidant characteristics in plasma in a study comparing three types of wine—description of two O-methylated derivatives of gallic acid in humans. Free Radic Res. 2003;37(9):1021–1035. PubMed

Cassano A, Conidi C, Ruby-Figueroa R, Castro-Muñoz R. Nanofiltration and tight ultrafiltration membranes for the recovery of polyphenols from agro-food by-products. Int J Mol Sci. 2018;19(2):351. PubMed PMC

Castro-Muñoz R, Fíla V. Membrane-based technologies as an emerging tool for separating high-added-value compounds from natural products. Trends Food Sci Technol. 2018;82:8–20.

Castro-Muñoz R, Yáñez-Fernández J, Fíla V. Phenolic compounds recovered from agro-food by-products using membrane technologies: an overview. Food Chem. 2016;213:753–762. PubMed

Castro-Muñoz R, Fíla V, Barragán-Huerta BE, Yáñez-Fernández J, Piña-Rosas JA, Arboleda-Mejía J. Processing of Xoconostle fruit (Opuntia joconostle) juice for improving its commercialization using membrane filtration. J Food Process Preserv. 2017

Castro-Muñoz R, Conidi C, Cassano A. Membrane-based technologies for meeting the recovery of biologically active compounds from foods and their by-products. Crit Rev Food Sci Nutr. 2018 PubMed

Castro-Muñoz R, De La Iglesia Ó, Fila V, Téllez C, Coronas J. Pervaporation-assisted esterification reactions by means of mixed matrix membranes. Ind Eng Chem Res. 2018;57:15998–16011.

Castro-Muñoz R, Galiano F, Fíla V, Drioli E, Figoli A. Mixed matrix membranes (MMMs) for ethanol purification through pervaporation: current state of the art. Rev Chem Eng. 2018

Catarino M, Mendes A. Dealcoholizing wine by membrane separation processes. Innov Food Sci Emerg Technol. 2011;12(3):330–337.

Catarino M, Mendes A. Non-alcoholic beer—a new industrial process. Sep Purif Technol. 2011;79(3):342–351.

Catarino M, Ferreira A, Mendes A. Study and optimization of aroma recovery from beer by pervaporation. J Membr Sci. 2009;341(1–2):51–59.

Chuntanalerg P, Kulprathipanja S, Chaisuwan T, Aungkavattana P, Hemra K, Wongkasemjit S. Performance polybenzoxazine membrane and mixed matrix membrane for ethanol purification via pervaporation applications. J Chem Technol Biotechnol. 2016;91(4):1173–1182.

Claes S, Vandezande P, Mullens S, Leysen R, De Sitter K, Andersson A, et al. High flux composite PTMSP-silica nanohybrid membranes for the pervaporation of ethanol/water mixtures. J Membr Sci. 2010;351(1–2):160–167.

Cleophas TJ. Wine, beer and spirits and the risk of myocardial infarction: a systematic review. Biomed Pharmacother. 1999;53(9):417–423. PubMed

Costanzo S, Di Castelnuovo A, Donati MB, Iacoviello L, de Gaetano G. Alcohol consumption and mortality in patients with cardiovascular disease. A meta-analysis. J Am Coll Cardiol. 2010;55(13):1339–1347. PubMed

Crespo J, Brazinha C. Fundamentals of pervaporation. In: Basile A, Figoli A, Khayet M, editors. Pervaporation, vapour permeation and membrane distillation: principles and applications. Cambridge: Elsevier; 2015. pp. 1–17.

Figoli A, Santoro S, Galiano F, Basile A. Pervaporation membranes: preparation, characterization, and application. In: Basile A, Figoli A, Khayet M, editors. Pervaporation, vapour permeation and membrane distillation. 1. Cambridge: Elsevier; 2015. pp. 281–304.

Galanakis CM. Emerging technologies for the production of nutraceuticals from agricultural by-products: a viewpoint of opportunities and challenges. Food Bioprod Process. 2013;91(4):575–579.

Galanakis CM. Separation of functional macromolecules and micromolecules: from ultrafiltration to the border of nanofiltration. Trends Food Sci Technol. 2015;42(1):44–63.

Galanakis CM, Kotanidis A, Dianellou M, Gekas V. Phenolic content and antioxidant capacity of Cypriot wines. Czech J Food Sci. 2015;33(2):126–136.

Gómez-Plaza E, López-Nicolás JM, López-Roca JM, Martínez-Cutillas A. Dealcoholization of wine. Behaviour of the aroma components during the process. LWT Food Sci Technol. 1999;32(6):384–386.

Gu J, Shi X, Bai Y, Zhang H, Zhang L, Huang H. Silicalite-filled polyether-block-amides membranes for recovering ethanol from aqueous solution by pervaporation. Chem Eng Technol. 2009;32(1):155–160.

Guilford JM, Pezzuto JM. Wine and health: a review. Am J Enol Viticult. 2011;62(4):471–486.

Hoof V, Van Abeele L, Buekenhoudt A, Dotremont C, Leysen R. Economic comparison between azeotropic distillation and different hybrid systems combining distillation with pervaporation for the dehydration of isopropanol. Sep Purif Technol. 2004;37:33–49.

Huang Y, Zhang P, Fu J, Zhou Y, Huang X, Tang X. Pervaporation of ethanol aqueous solution by polydimethylsiloxane/polyphosphazene nanotube nanocomposite membranes. J Membr Sci. 2009;339(1–2):85–92.

Le NL, Wang Y, Chung TS. Pebax/POSS mixed matrix membranes for ethanol recovery from aqueous solutions via pervaporation. J Membr Sci. 2011;379(1–2):174–183.

Lehnert R, Novák P, Macieira F, Kuřec M, Teixeira JA, Brányik T. Optimisation of lab-scale continuous alcohol-free beer production. Czech J Food Sci. 2009;27(4):267–275.

Li Y, Wee LH, Martens J, Vankelecom IFJ. ZIF-71 as a potential filler to prepare pervaporation membranes for bio-alcohol recovery. J Mater Chem A. 2014;2:10034–10040.

Liguori L, De Francesco G, Russo P, Perretti G, Albanese D, Di Matteo M. Quality attributes of low-alcohol top-fermented beers produced by membrane contactor. Food Bioprocess Technol. 2016;9(1):191–200.

Liguori L, Russo P, Albanese D, Di Matteo M. Production of low-alcohol beverages: current status and perspectives, food processing for increased quality and consumption. Amsterdam: Elsevier Inc.; 2018.

Lipnizki F. Beer dealcoholization. In: Drioli E, Giorno L, editors. Encyclopedia of membranes. 1. Berlin: Springer; 2014. pp. 1–2.

Lipnizki F, Olsson J, Trägårdh G. Scale-up of pervaporation for the recovery of natural aroma compounds in the food industry part 2: optimisation and integration. J Food Eng. 2002;54(3):197–205.

Liu X, Hu D, Li M, Zhang J, Zhu Z, Zeng G, et al. Preparation and characterization of silicalite-1/PDMS surface sieving pervaporation membrane for separation of ethanol/water mixture. J Appl Polym Sci. 2015;132(34):1–11. PubMed

Lugasi A, Hóvári J. Antioxidant properties of commercial alcoholic and nonalcoholic beverages. Nahrung/Food. 2003;47(2):79–86. PubMed

Mangindaan D, Khoiruddin K, Wenten IG. Beverage dealcoholization processes: past, present, and future. Trends Food Sci Technol. 2018;71:36–45.

Mohammadi T, Aroujalian A, Bakhshi A. Pervaporation of dilute alcoholic mixtures using PDMS membrane. Chem Eng Sci. 2005;60(7):1875–1880.

Müller M, Bellut K, Tippmann J, Becker T. Physical methods for dealcoholization of beverage matrices and their impact on quality attributes. ChemBioEng Rev. 2017;5:310–326.

Naik PV, Verlooy PLH, Smet S, Martens JM, Vankelecom IFJ. PDMS mixed matrix membranes filled with novel PSS-2 nanoparticles for ethanol/water separation by pervaporation. RSC Adv. 2016;6:78648–78651.

Naik PV, Kerkhofs S, Martens JA, Vankelecom IFJ. PDMS mixed matrix membranes containing hollow silicalite sphere for ethanol/water separation by pervaporation. J Membr Sci. 2016;502:48–56.

Nardini M, Natella F, Scaccini C, Ghiselli A. Phenolic acids from beer are absorbed and extensively metabolized in humans. J Nutr Biochem. 2006;17(1):14–22. PubMed

Nardini M, Forte M, Vrhovsek U, Mattivi F, Viola R, Scaccini C. White wine phenolics are absorbed and extensively metabolized in humans. J Agric Food Chem. 2009;57(7):2711–2718. PubMed

Olaniran AO, Hiralal L, Mokoena MP, Pillay B. Flavour-active volatile compounds in beer: production, regulation and control. J Inst Brew. 2017;123(1):13–23.

Olmo Á, Blanco CA, Palacio L, Prádanos P, Hernández A. Pervaporation methodology for improving alcohol-free beer quality through aroma recovery. J Food Eng. 2014;133:1–8.

Paixão N, Perestrelo R, Marques JC, Câmara JS. Relationship between antioxidant capacity and total phenolic content of red, rosé and white wines. Food Chem. 2007;105(1):204–214.

Partanen TJ, Vainio HU, Ojajärvi IA, Kauppinen TP. Pancreas cancer, tobacco smoking and consumption of alcoholic beverages: a case-control study. Cancer Lett. 1997;116(1):27–32. PubMed

Purwasasmita M, Kurnia D, Mandias FC, Wenten K. Beer dealcoholization using non-porous membrane distillation. Food Bioprod Process. 2015;94:180–186.

Raisi A, Aroujalian A, Kaghazchi T. A predictive mass transfer model for aroma compounds recovery by pervaporation. J Food Eng. 2009;95(2):305–312.

Saffarionpour S, Ottens M. Recent advances in techniques for flavor recovery in liquid food processing. Food Eng Rev. 2018;10(2):81–94.

Salgado CM, Fernández-Fernández E, Palacio L, Carmona FJ, Hernández A, Prádanos P. Application of pervaporation and nanofiltration membrane processes for the elaboration of full flavored low alcohol white wines. Food Bioprod Process. 2017;101:11–21.

Samanta HS, Ray SK. Separation of ethanol from water by pervaporation using mixed matrix copolymer membranes. Sep Purif Technol. 2015;146:176–186.

Schmidtke LM, Blackman JW, Agboola SO. Production technologies for reduced alcoholic wines. J Food Sci. 2012;77(1):25–41. PubMed

Sohrabvandi S, Mousavi SM, Razavi SH, Mortazavian AM, Rezaei K. Alcohol-free beer: methods of production, sensorial defects, and healthful effects. Food Rev Int. 2010;26(4):335–352.

Sohrabvandi S, Mousavi S, Razavi S, Mortazavian A, Issn S, Amir M. Bacteria in beer viability of probiotic bacteria in low alcohol-and non-alcoholic beer during refrigerated storage. Philipp Agric Sci. 2010;93(1):104–108.

Sohrabvandi S, Mortazavian AM, Rezaei K. Health-related aspects of beer: a review. Int J Food Prop. 2012;15(2):350–373.

Solov AM. Global production and consumption of alcoholic beverages. Stud Russ Econ Dev. 2018;29(1):102–108.

Statista (2018) Alcoholic beverages consumption. Retrieved September 15, 2018, from https://www.statista.com/

Strejc J, Siristova L, Karabin M, Almeida JB, Branyik T. Production of alcohol-free beer with elevated amounts of flavouring compounds using lager yeast mutants. J Inst Brew. 2013;119(3):149–155.

Sun D, Li BB, Xu ZL. Pervaporation of ethanol/water mixture by organophilic nano-silica filled PDMS composite membranes. Desalination. 2013;322:159–166.

Takács L, Vatai G, Korány K. Production of alcohol free wine by pervaporation. J Food Eng. 2007;78(1):118–125.

Tan SJ, Xiao ZY, Li L, Wu FW, Xu ZH, Zhang ZB. Experimental research on dealcoholization of wine by pervaporation. Jingxi Huagong/Fine Chem. 2003;20(2):69–79.

van Golde P, Sloots L, Vermeulen W, Wielders J, Hart H, Bonno B, van de Wiel A. The role of alcohol in the anti low density lipoprotein oxidation activity of red wine. Atherosclerosis. 1999;147:365–370. PubMed

Wee SL, Tye CT, Bhatia S. Membrane separation process-pervaporation through zeolite membrane. Sep Purif Technol. 2008;63(3):500–516.

WHO (2011) Global status report on alcohol and health. Geneva, Switzerland

Wijmans JG, Baker RW. The solution–diffusion model: a review. J Membr Sci. 1995;107(1–2):1–21.

Yadav A, Lind ML, Ma X, Lin YS. Nanocomposite silicalite-1/polydimethylsiloxane membranes for pervaporation of ethanol from dilute aqueous solutions. Ind Eng Chem Res. 2013;52:5207–5212.

Zhan X, Lu J, Tan T, Li J. Mixed matrix membranes with HF acid etched ZSM-5 for ethanol/water separation: preparation and pervaporation performance. Appl Surf Sci. 2012;259:547–556.

Zhang G, Li J, Wang N, Fan H, Zhang R, Zhang G, Ji S. Enhanced flux of polydimethylsiloxane membrane for ethanol permselective pervaporation via incorporation of MIL-53 particles. J Membr Sci. 2015;492:322–330.

Zhou H, Su Y, Chen X, Wan Y. Separation of acetone, butanol and ethanol (ABE) from dilute aqueous solutions by silicalite-1/PDMS hybrid pervaporation membranes. Sep Purif Technol. 2011;79(3):375–384.

Recent innovations in the production of selected specialty (non-traditional) beers