We herein present an overview of the upcoming 5th edition of the World Health Organization Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid and histiocytic neoplasms will be presented in a separate accompanying article. Besides listing the entities of the classification, we highlight and explain changes from the revised 4th edition. These include reorganization of entities by a hierarchical system as is adopted throughout the 5th edition of the WHO classification of tumours of all organ systems, modification of nomenclature for some entities, revision of diagnostic criteria or subtypes, deletion of certain entities, and introduction of new entities, as well as inclusion of tumour-like lesions, mesenchymal lesions specific to lymph node and spleen, and germline predisposition syndromes associated with the lymphoid neoplasms.

Amsterdam UMC location Vrije Universiteit Amsterdam Department of Pathology Amsterdam The Netherlands

Anatomic Pathology Department and Translational Hematopathology Lab Valdecilla IDIVAL University Hospital Santander Spain

Center for Genomic and Computational Biology and Department of Medicine Duke University Durham NC USA

Centre for Haemato Oncology Barts Cancer institute QMUL and SIHMDS Barts Health NHS Trust London UK

Department of Clinical Pathology Robert Bosch Krankenhaus and Dr Margarete Fischer Bosch Institute of Clinical Pharmacology Stuttgart Germany

Department of Dermatology Northwestern University Feinberg Medical School Chicago IL USA

Department of Dermatology Venereology and Allergology University Medical Center Göttingen Göttingen Germany

Department of Hematopathology Division of Pathology and Laboratory Medicine The University of Texas MD Anderson Cancer Center Houston TX USA

Department of Histopathology Royal Marsden Hospital London UK

Department of Laboratory Medicine and Pathology Mayo Clinic Rochester MN USA

Department of Medical Biotechnology University of Siena Siena Italy

Department of Oncology University of Oxford Oxford UK

Department of Pathology Aga Khan University Hospital Nairobi Nairobi Kenya

Department of Pathology and Cell Biology Columbia University Irving Medical Center New York NY USA

Department of Pathology and Immunology Baylor College of Medicine and Texas Children's Hospital Houston TX USA

Department of Pathology and Laboratory Medicine Children's Hospital Los Angeles Los Angeles CA USA

Department of Pathology and Laboratory Medicine Indiana University Indianapolis IN USA

Department of Pathology and Laboratory Medicine Memorial Sloan Kettering Cancer Center New York NY USA

Department of Pathology and Laboratory Medicine Nagoya Japan

Department of Pathology and Laboratory Medicine University of California Los Angeles Los Angeles CA USA

Department of Pathology and Laboratory Medicine University of Pennsylvania Philadelphia PA USA

Department of Pathology and Laboratory Medicine Weill Cornell Medicine New York NY USA

Department of Pathology Bordeaux University Hospital Bordeaux France

Department of Pathology Boston Children's Hospital Boston MA USA

Department of Pathology Charles University Prague Faculty of Medicine in Plzen Plzen Czech Republic

Department of Pathology Chi Mei Medical Center Tainan Taiwan

Department of Pathology Federal University of Bahia Salvador Brazil

Department of Pathology Fudan University Shanghai Cancer Center Shanghai China

Department of Pathology Hematopathology Section and Lymph Node Registry University Hospital Schleswig Holstein University of Kiel Kiel Germany

Department of Pathology Hopital Haut Lévêque CHU Bordeaux Pessac France

Department of Pathology Institut Paoli Calmettes and Aix Marseillreference University Marseille France

Department of Pathology Massachusetts General Hospital and Harvard Medical School Boston MA USA

Department of Pathology Medical College of Wisconsin and Children's Wisconsin Milwaukee WI USA

Department of Pathology Queen Elizabeth Hospital Kowloon Hong Kong

Department of Pathology Stanford University School of Medicine Stanford CA USA

Department of Pathology Tata Memorial Hospital Mumbai India

Department of Pathology The University of Alabama at Birmingham Birmingham AL USA

Department of Pathology University of Miami Miami FL USA

Department of Pathology University of Michigan Ann Arbor MI USA

Department of Pathology West China Hospital Sichuan University Chengdu China

Department of Pathology Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore

Department of Virology Nagoya University Graduate School of Medicine Nagoya Japan

Departments of Pathology and Genomic Medicine The University of Texas MD Anderson Cancer Center Houston TX USA

Division of Cellular and Molecular Pathology Department of Pathology University of Cambridge Cambridge UK

Division of Haematology and Immunology Leeds Institute of Medical Research University of Leeds Leeds UK

Division of Hematology Mayo Clinic Rochester Minnesota Rochester MN USA

Division of Hematology Mayo Clinic Rochester MN USA

Division of Histopathology SL Raheja Hospital Mumbai India

Division of Nephrology and Hypertension Division of Hematology Mayo Clinic Rochester MN USA

Dr Senckenberg Institute of Pathology Goethe University Frankfurt Frankfurt am Main Germany

Hematology Oncology Universitätsklinikum Jena Jena Germany

HMDS Leeds Cancer Centre Leeds Teaching Hospitals NHS Trust Leeds UK

Hospices Civils de Lyon Department of Pathology Université Lyon 1 Centre International de Recherche en Infectiologie INSERM U1111 CNRS UMR5308 Lyon France

Immunology Division Garvan Institute of Medical Research Sydney Australia

Institute of Human Genetics Ulm University and Ulm University Medical Center Ulm Germany

Institute of Pathology Julius Maximilians Universität Würzburg Würzburg Germany

Kempf und Pfaltz Histologische Diagnostik Zurich and Department of Dermatology University Hospital Zurich Zurich Switzerland

Leiden University Medical Center Department of Pathology Leiden The Netherlands

Liverpool Clinical Laboratories Liverpool University Hospitals Foundation Trust Liverpool UK

MD PhD DITEP Gustave Roussy Villejuif France

National Amyloidosis Centre University College London London UK

National University Cancer Institute Singapore Singapore

Pathology Unit Department of Laboratories Bambino Gesu Children's Hospital IRCCS Rome Italy

Section of Hematology Oncology University of Chicago Chicago IL USA

Section of Pathology Clinical Research Division Fred Hutchinson Cancer Center Seattle WA USA

Translational and Clinical Research Institute Newcastle University Centre for Cancer Faculty of Medical Sciences Newcastle University Newcastle upon Tyne UK

University of Milan Fondazione Cà Granda IRCCS Ospedale Maggiore Policlinico Milan Italy

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