The plant hormone kinetin in disease therapy and healthy aging
Language English Country Great Britain, England Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
31479763
DOI
10.1016/j.arr.2019.100958
PII: S1568-1637(19)30164-3
Knihovny.cz E-resources
- Keywords
- Age-related diseases, Aging, Cytokinin, Kinetin,
- MeSH
- Cytokinins MeSH
- Kinetin pharmacology therapeutic use MeSH
- Humans MeSH
- Aging * MeSH
- Healthy Aging * MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Cytokinins MeSH
- Kinetin MeSH
It has been more than 60 years since the discovery of kinetin, the first known member of a group of plant hormones called cytokinins. In this review we summarize the health-promoting activity of kinetin in animal systems, ranging from cells cultured in vitro through invertebrates to mammals. Kinetin has been shown to modulate aging, to delay age-related physiological decline and to protect against some neurodegenerative diseases. We also review studies on its mechanism of action, as well as point out gaps in our current knowledge.
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