Changes in Cognitive Impairment in the Czech Republic
Language English Country United States Media print
Document type Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't
PubMed
31609688
DOI
10.3233/jad-190688
PII: JAD190688
Knihovny.cz E-resources
- Keywords
- Alzheimer’s disease, Czech Republic, cognitive impairment, epidemiology, prevalence, trends,
- MeSH
- Cognitive Dysfunction diagnosis epidemiology psychology MeSH
- Humans MeSH
- Longitudinal Studies MeSH
- Prospective Studies MeSH
- Independent Living trends MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Aging pathology psychology MeSH
- Health Surveys trends MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Multicenter Study MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Czech Republic epidemiology MeSH
BACKGROUND: Studies from North America and Western Europe suggest stable or declining trends in impaired cognition across birth cohorts. OBJECTIVE: We aimed to examine changes in the age-specific prevalence of cognitive impairment in the Czech Republic. METHODS: The study used two samples from the population-based Czech Survey on Health, Ageing and Retirement in Europe. Age-specific prevalence of cognitive impairment (defined based on scores in verbal fluency, immediate recall, delayed recall, and temporal orientation) was compared between participants in wave 2 (2006/2007; n = 1,107) and wave 6 (2015; n = 3,104). Logistic regression was used to estimate the association between the wave and cognitive impairment, step-wise adjusting for sociodemographic and clinical characteristics. Multiple sensitivity analyses, focusing on alternative operationalizations of relative cognitive impairment, impact of missing cognitive data, and survival bias, were carried out. RESULTS: The most conservative estimate suggested that the age-specific prevalence of cognitive impairment declined by one fifth, from 11% in 2006/2007 to 9% in 2015. Decline was observed in all sensitivity analyses. The change was associated with differences in physical inactivity, management of high blood cholesterol, and increases in length education. CONCLUSION: Older adults in the Czech Republic, a country situated in the Central and Eastern European region, have achieved positive developments in cognitive aging. Longer education, better management of cardiovascular factors, and reduced physical inactivity seem to be of key importance.
Aging Research Center Karolinska Institutet and Stockholm University Stockholm Sweden
Charles University Prague 3rd Faculty of Medicine Prague Czech Republic
Charles University Prague Faculty of Science Prague Czech Republic
Department of Public Health Sciences Karolinska Institutet Stockholm Sweden
National Institute of Mental Health Klecany Czech Republic
University of Groningen Faculty of Medical Sciences Groningen Netherlands
References provided by Crossref.org
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