Botulinum Toxin as a Biological Warfare Agent: Poisoning, Diagnosis and Countermeasures
Language English Country Netherlands Media print
Document type Journal Article, Review
PubMed
32108007
DOI
10.2174/1389557520666200228105312
PII: MRMC-EPUB-104901
Knihovny.cz E-resources
- Keywords
- Acetylcholine, Clostridium botulinum, antiserum, biological warfare agent, botulinum toxin, botulism, detection, diagnosis, poisoning.,
- MeSH
- Biological Warfare Agents * MeSH
- Botulism diagnosis therapy MeSH
- Botulinum Toxins poisoning MeSH
- Humans MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
- Names of Substances
- Biological Warfare Agents * MeSH
- Botulinum Toxins MeSH
Botulinum toxin is a neurotoxin produced by Clostridium botulinum and some other relative species. It causes a lethal disease called botulism. It can enter the body via infections by Clostridium (e.g. wound and children botulism) or by direct contact with the toxin or eating contaminated food (food-borne botulism). Botulinum toxin is also considered as a relevant biological warfare agent with an expected high number of causalities when misused for bioterrorist or military purposes. The current paper surveys the actual knowledge about botulinum toxin pathogenesis, the manifestation of poisoning, and current trends in diagnostics and therapeutics. Relevant and recent literature is summarized in this paper.
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