Excessive alcohol consumption is the cause of several diseases and thus is of a major concern for society. Worldwide alcohol consumption has increased by many folds over the past decades. This urgently calls for intervention and relapse counteract measures. Modern pharmacological solutions induce complete alcohol self-restraint and prevent relapse, but they have many side effects. Natural products are most promising as they cause fewer adverse effects. Here we discuss in detail the medicinal plants used in various traditional/folklore medicine systems for targeting alcohol abuse. We also comprehensively describe preclinical and clinical studies done on some of these plants along with the possible mechanisms of action.

Centre for Biodiversity Conservation and Management G B Pant National Institute of Himalayan Environment and Sustainable Development Almora India

Department Global R and D NTZ Lab Ltd Sofia Bulgaria

Department of Environmental Sciences Faculty of Chemistry and Biology Universidad de Santiago de Chile Santiago Chile

Department of Pharmaceutical Botany Iuliu Hațieganu University of Medicine and Pharmacy Cluj Napoca Romania

Department of Pharmaceutical Sciences Faculty of Technology Kumaun University Bhimtal Campus Nainital India

Department of Pharmacognosy School of Pharmaceutical Sciences Lovely Professional University Phagwara India

Department of Pharmacognosy University of Vienna Vienna Austria

Department of Public Health Xi'an Jiaotong Liverpool University Suzhou China

Faculty of Chemistry Wrocław University of Science and Technology Wybrzeże Wyspiańskiego Wrocław Poland

Institute of Genetics and Animal Breeding of the Polish Academy of Sciences Jastrzebiec Poland

Institute of Molecular Biology Roumen Tsanev Department of Biochemical Pharmacology and Drug Design Bulgarian Academy of Sciences Sofia Bulgaria

Institute of Molecular Genetics Academy of Sciences of the Czech Republic Division BIOCEV Prague Czechia

Institute of Neurobiology Bulgarian Academy of Sciences Sofia Bulgaria

Ludwig Boltzmann Institute for Digital Health and Patient Safety Medical University of Vienna Vienna Austria

School of Medical Sciences Universiti Sains Malaysia Kota Bharu Malaysia

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