Renal and Bladder Cancer During Pregnancy: A Review of 47 Cases and Literature-based Recommendations for Management
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu časopisecké články
PubMed
33203520
DOI
10.1016/j.urology.2020.08.084
PII: S0090-4295(20)31271-1
Knihovny.cz E-zdroje
- MeSH
- bolest etiologie MeSH
- dospělí MeSH
- hematurie etiologie MeSH
- indukovaný porod MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladý dospělý MeSH
- nádorové komplikace v těhotenství * mortalita terapie MeSH
- nádory ledvin * mortalita terapie MeSH
- nádory močového měchýře * mortalita terapie MeSH
- novorozenec MeSH
- předčasný porod MeSH
- registrace MeSH
- retrospektivní studie MeSH
- těhotenství MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladý dospělý MeSH
- novorozenec MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
OBJECTIVE: To provide contemporary gestational age-specific recommendations for management, a retrospective series of patients with renal or bladder cancer during pregnancy is reported. METHODS: Obstetric and oncological data of pregnant patients with a diagnosis of renal or bladder cancer were selected from the worldwide registry of the International Network of Cancer, Infertility and Pregnancy. In addition, the literature was reviewed for recent case reports since last reviews in 2014 for renal cancer and 2004 for bladder cancer. RESULTS: International Network of Cancer, Infertility and Pregnancy registered 22 cases (14 renal cancer and 8 bladder cancer), diagnosed between 1999 and 2017, and the literature reported 15 cases with renal cancer and 10 cases with bladder cancer between 2004 and 2019. Most common symptoms for renal and bladder cancer were pain (28%) and hematuria (66%), respectively. In more than half of the patients, surgical treatment was performed during pregnancy. Preterm deliveries were mostly medically induced (12 of 17, 71%) and all patients with a planned delivery before 34 weeks had advanced cancer. For renal and bladder cancer respectively, 79% and 87% of patients obtained complete remission. Advanced cancer stages had worse prognosis; 3 of 7 patients with known follow-up deceased within 15 months after diagnosis. CONCLUSION: Gestational age at diagnosis determines further management of renal and bladder cancers during pregnancy. Advanced stages challenge decision-making. The maternal needs for immediate treatment, and the neonatal risks including the impact of a preterm delivery should be discussed in a multidisciplinary setting while respecting the patient's autonomy.
Clinic of Obstetrics and Gynecology University of Milan Bicocca San Gerardo Hospital Monza Italy
Department of Gynecological Oncology Amsterdam University Medical Centres Amsterdam The Netherlands
Department of Obstetrics and Gynecology Cooper University Health Care Camden New Jersey USA
Department of Obstetrics Cliniques Universitaires St Luc UCL Sint Lambrechts Woluwe Belgium
Department of Urology University Hospitals Leuven Leuven Belgium
Department Surgical Sciences University of Torino Torino Italy
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