Titanium and its alloys belong to the group of materials used in implantology due to their biocompatibility, outstanding corrosion resistance and good mechanical properties. However, the value of Young's modulus is too high in comparison with the human bone, which could result in the failure of implants. This problem can be overcome by creating pores in the materials, which, moreover, improves the osseointegration. Therefore, TiSi2 and TiSi2 with 20 wt.% of the pore-forming agent (PA) were prepared by reactive sintering and compared with pure titanium and titanium with the addition of various PA content in this study. For manufacturing implants (especially augmentation or spinal replacements), titanium with PA seemed to be more suitable than TiSi2 + 20 wt.% PA. In addition, titanium with 30 or 40 wt.% PA contained pores with a size allowing bone tissue ingrowth. Furthermore, Ti + 30 wt.% PA was more suitable material in terms of corrosion resistance; however, its Young's modulus was higher than that of the human bone while Ti + 40 wt.% PA had a Young's modulus close to the human bone.

Department of Biochemistry and Microbiology University of Chemistry and Technology Prague Technická 5 166 28 Prague 6 Czech Republic

Department of Glass and Ceramics University of Chemistry and Technology Prague Technická 5 166 28 Prague 6 Czech Republic

Department of Metals and Corrosion Engineering University of Chemistry and Technology Prague Technická 5 166 28 Prague 6 Czech Republic

UJP Praha a s Nad Kamínkou 1345 156 10 Prague 16 Zbraslav Czech Republic

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