Analysing the attributes of Comprehensive Cancer Centres and Cancer Centres across Europe to identify key hallmarks

. 2021 May ; 15 (5) : 1277-1288. [epub] 20210330

Jazyk angličtina Země Spojené státy americké Médium print-electronic

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/pmid33734563

There is a persistent variation in cancer outcomes among and within European countries suggesting (among other causes) inequalities in access to or delivery of high-quality cancer care. European policy (EU Cancer Mission and Europe's Beating Cancer Plan) is currently moving towards a mission-oriented approach addressing these inequalities. In this study, we used the quantitative and qualitative data of the Organisation of European Cancer Institutes' Accreditation and Designation Programme, relating to 40 large European cancer centres, to describe their current compliance with quality standards, to identify the hallmarks common to all centres and to show the distinctive features of Comprehensive Cancer Centres. All Comprehensive Cancer Centres and Cancer Centres accredited by the Organisation of European Cancer Institutes show good compliance with quality standards related to care, multidisciplinarity and patient centredness. However, Comprehensive Cancer Centres on average showed significantly better scores on indicators related to the volume, quality and integration of translational research, such as high-impact publications, clinical trial activity (especially in phase I and phase IIa trials) and filing more patents as early indicators of innovation. However, irrespective of their size, centres show significant variability regarding effective governance when functioning as entities within larger hospitals.

Zobrazit více v PubMed

Ferlay J, Colombet M, Soerjomataram I, Dyba T, Randi G, Bettio M, Gavin A, Visser O & Bray F (2018) Cancer incidence and mortality patterns in Europe: Estimates for 40 countries and 25 major cancers in 2018. Eur J Cancer 103, 356–387. PubMed

European Commission. Conquering cancer: Mission Possible. Interim Report of the Mission Board for Cancer. Publications office of the European Union, Luxembourg, 2020. https://op.europa.eu/en/web/eu‐law‐and‐publications/publication‐detail/‐/publication/d0235612‐b68a‐11ea‐bb7a‐01aa75ed71a1 (accessed 26 June 2020).

Oberst S (2019) Bridging research and clinical care ‐ the comprehensive cancer centre. Mol Oncol 13, 614–618. PubMed PMC

Berns A, Ringborg U, Celis JE, Heitor M, Aaronson NK, Abou‐Zeid N, Adami H‐O, Apostolidis K, Baumann M, Bardelli A et al., (2020) Towards a cancer mission in Horizon Europe: recommendations. Mol Oncol 14, 1589–1615. PubMed PMC

Berns A, Ringborg U, Eggermont A, Baumann M, Calvo F, Eggert A, Espina C, Hanahan D, Lacombe D, Lorenzo F et al., (2019) Towards a Cancer Mission in Horizon Europe. Mol Oncol 13, 2301–2304. PubMed PMC

Celis JE & Heitor M (2019) Towards a mission‐oriented approach to cancer in Europe: an unmet need in cancer research policy. Mol Oncol 13, 502–510. PubMed PMC

Philip T, Karjalainen S, De Lorenzo F, Apostolidis K, Lombardo C, Nilbert M, Lacombe D, Poortmans P, Albreht T, Kearns P et al., (2019) What could be a cancer mission objective if we join our forces in the fight against cancer? Tumori J 105, 447–455. PubMed PMC

Albreht T, Kiasuwa R & Va den Bulcke M. European Guide on Quality Improvement in Comprehensive Cancer Control. CanCon – Cancer Control Joint Action. National and University Library. Ljubljana, Slovenia, 2017.

European Commission . Europe’s Beating Cancer Plan. Brussels, 2021. (accessed on 11 Feb 2021) https://ec.europa.eu/commission/presscorner/detail/en/ip_21_342.

UICC‐CICA (1978) Guidelines for Developing a Comprehensive Cancer Centre. UICC, Geneva.

Saghatchian M, Thonon F, Boomsma F et al., (2014) Pioneering quality assessment in European Cancer Centres: a data analysis of the organization for European Cancer. J Oncol Pract 10, e342–349. PubMed

Nathan D & Benz EJ (2001) Comprehensive Cancer Centres and the war on cancer. Nat Rev Cancer 1, 240–245. PubMed

NIH Funding Opportunities and Notices (2020) National Institutes of Health (NIH) ‐ National Cancer Institute (NCI). Cancer Center Support Grants (CCSGs) for NCI‐designated Cancer Centers. (accessed on 24 November 2020) https://grants.nih.gov/grants/guide/pa‐files/PAR‐20‐043.html.

Deutsche KrebsHilfe (2017) Program for the Development of Interdisciplinary Oncology Centres of Excellence in Germany Table of Contents Introduction/Criteria for Funding. https://www.krebshilfe.de/fileadmin/Downloads/PDFs/Foerderung/CCCs_7th_call/Ausschreibung_Leitfaden_7._Call__08_Sep_2017.pdfaccessed on 24 November 2020 .

Ringborg U, Celis J, Eggermont A & Berns A (2018) The European Academy of Cancer Sciences – Designation of Comprehensive Cancer Centres of Excellence. Eur J Cancer 93, 138–139. PubMed

van Putten M, Nelen SD, Lemmens VEPP, Stoot JHMB, Hartgrink HH, Gisbertz SS, Spillenaar Bilgen EJ, Heisterkamp J, Verhoeven RHA & Nieuwenhuijzen GAP (2018) Overall survival before and after centralization of gastric cancer surgery in the Netherlands. Br J Surg. 105, 1807–1815. PubMed

Pfister DG, Rubin DM, Elkin EB, Neill US, Duck E, Radzyner M & Bach PB (2015) Risk Adjusting Survival Outcomes in Hospitals That Treat Patients With Cancer Without Information on Cancer Stage. JAMA Oncol 1, 1303–1310. PubMed PMC

Wolfson JA, Sun CL, Wyatt LP, Hurria A & Bhatia S (2015) Impact of care at comprehensive cancer centers on outcome: Results from a population‐based study. Cancer 121, 3885–3893. PubMed PMC

Begg CB, Cramer LD, Hoskins WJ et al., (1998) Impact of hospital volume on operative mortality for major cancer surgery. JAMA 280, 1747–1751. PubMed

Birkmeyer NJO, Goodney PP, Stukel TA, Hillner BE & Birkmeyer JD (2005) Do cancer centers designated by the National Cancer Institute have better surgical outcomes? Cancer 103, 435–441. PubMed

Fong Y, Gonen M, Rubin D, Radzyner M & Brennan MF (2005) Long‐term survival is superior after resection for cancer in high‐volume centers. Ann Surg 242, 540–547. PubMed PMC

Blay JY, Honoré C, Stoeckle E, Meeus P, Jafari M, Gouin F, Anract P, Ferron G, Rochwerger A, Ropars M et al., (2019) Surgery in reference centers improves survival of sarcoma patients: a nationwide study. Ann Oncol 30, 1143–1153. PubMed PMC

Haj Mohammad N, Bernards N, Besselink MG, Busch OR, Wilmink JW, Creemers GJM, De Hingh IHJT, Lemmens VEPP& van Laarhoven HWM (2016) Volume matters in the systemic treatment of metastatic pancreatic cancer: a population‐based study in the Netherlands. J Cancer Res Clin Oncol. 142, 1353–1360. PubMed PMC

Bristow RE, Chang J, Ziogas A, Campos B, Chavez LR & Anton‐Culver H (2015) Impact of National Cancer Institute Comprehensive Cancer Centers on ovarian cancer treatment and survival. J Am Coll Surg 220, 940–950. PubMed PMC

Merkow RP, Yang AD, Pavey E, Song M‐W, Chung JW, Bentrem DJ & Bilimoria KY (2019) Comparison of hospitals affiliated with PPS‐exempt cancer centers, other hospitals affiliated with NCI‐designated cancer centers, and other hospitals that provide cancer care. JAMA Intern Med 179, 1043–1051. PubMed PMC

Sullivan R (2009) Has the US Cancer Centre model been 'successful'? Lessons for the European cancer community. Mol Oncol 3, 192–203. PubMed PMC

Kowalksi C, Graeven U, von Kalle C, Lang H, Beckmann MW, Blohmer J‐U, Burchardt M, Ehrenfeld M, Fichtner J, Grabbe S et al., (2017) Shifting cancer care towards Multidisciplinarity: the cancer center certification program of the German Cancer Society. BMC Cancer 17, 850. PubMed PMC

Oberst S, van Harten W, Sæter G, de Paoli P, Nagy P, Burrion J‐B, Lovey J & Philip T (2020) 100 European core quality standards for cancer care and research centres. Lancet Oncol 21, 1009–1011. PubMed

OECI. – Accreditation and Designation User Manual v2.0, 2015 . OECI.‐EEIG – Publisher D/2015/12.243/1 – ISBN N. 9789080625693

https://www.oeci.eu/Attachments/OECI_ACC_Manual_2_0.pdf (accessed on 29 June, 2020)

OECD . Purchasing Power parities (PPP) (indicator), 2020. Available at: https://stats.OECD.org/Index.aspx?DataSetCode=SNA_TABLE4 (Accessed: 5 May 2020)

Unger JM, Cook E, Tai E & Bleyer A (2016) The role of clinical trial participation in cancer research: barriers, evidence, and strategies. Am Soc Clin Oncol Educ Book 35, 185–198. PubMed PMC

Oberst S, Boomsma F, Lombardo C, Docter M, Blaauwgeers H, De Paoli P, de Valeriola D, Paradiso A & Saghatchian M (2015) Participation of Italian Cancer Centres of the Alleanza Contro Il Cancro (ACC) in the Organisation of European Cancer Institutes (OECI) Accreditation and Designation program: a successful first national initiative. Tumori Journal 101, S6–9. PubMed

Najít záznam

Citační ukazatele

Možnosti archivace