The latest outbreak of a coronavirus disease in 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), evolved into a worldwide pandemic with massive effects on health, quality of life, and economy. Given the short period of time since the outbreak, there are several knowledge gaps on the comparative and zoonotic aspects of this new virus. Within the One Health concept, the current EAACI position paper dwells into the current knowledge on SARS-CoV-2's receptors, symptoms, transmission routes for human and animals living in close vicinity to each other, usefulness of animal models to study this disease and management options to avoid intra- and interspecies transmission. Similar pandemics might appear unexpectedly and more frequently in the near future due to climate change, consumption of exotic foods and drinks, globe-trotter travel possibilities, the growing world population, the decreasing production space, declining room for wildlife and free-ranging animals, and the changed lifestyle including living very close to animals. Therefore, both the society and the health authorities need to be aware and well prepared for similar future situations, and research needs to focus on prevention and fast development of treatment options (medications, vaccines).

Comparative Medicine Interuniversity Messerli Research Institute University of Veterinary Medicine and Medical University Vienna Vienna Austria

Department of Microbiology and Immunology Faculty of Veterinary Medicine Cairo University Cairo Egypt

Department of Paediatric Allergy and Pulmonology The Medical University of Warsaw Warsaw Poland

Faculty of Science Charles University Prague Czech Republic

Institute of Pathophysiology and Allergy Research Center of Pathophysiology Infectiology and Immunology Medical University of Vienna Vienna Austria

Medizinische Kleintierklinik Zentrum für Klinische Tiermedizin LMU Munich Germany

Swiss Institute of Allergy and Asthma Research University of Zurich Zurich Switzerland

Transylvania University Brasov Romania

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