How Are Infants Suspected to Have Cow's Milk Allergy Managed? A Real World Study Report
Language English Country Switzerland Media electronic
Document type Journal Article, Multicenter Study
PubMed
34578905
PubMed Central
PMC8464701
DOI
10.3390/nu13093027
PII: nu13093027
Knihovny.cz E-resources
- Keywords
- CoMiSS, amino acid formula, cow’s milk allergy, extensive hydrolysate, partial hydrolysate,
- MeSH
- Allergens immunology MeSH
- Milk Hypersensitivity diagnosis therapy MeSH
- Infant MeSH
- Humans MeSH
- Milk Proteins immunology MeSH
- Milk immunology MeSH
- Infant, Newborn MeSH
- Primary Health Care methods MeSH
- Prospective Studies MeSH
- Surveys and Questionnaires MeSH
- Animals MeSH
- Check Tag
- Infant MeSH
- Humans MeSH
- Male MeSH
- Infant, Newborn MeSH
- Female MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Multicenter Study MeSH
- Geographicals
- Belgium MeSH
- Czech Republic MeSH
- Germany MeSH
- United Kingdom MeSH
- Names of Substances
- Allergens MeSH
- Milk Proteins MeSH
The purpose of this study was to evaluate the diagnosis and management of infants presenting with symptoms attributable to cow's milk allergy (CMA) in a real life setting and to test how the Cow's Milk-related Symptom Score (CoMiSS®) can be used to support the awareness to diagnose cow's milk protein allergy in primary care practice. The CoMiSS is an awareness tool based on various symptoms such as crying, gastrointestinal symptoms, dermatological and respiratory symptoms. The study was conducted on 268 infants from four countries (Belgium, Czech Republic, Germany, UK) aged 0 to 18 months consulting for CMA related symptoms. The analysis was based on two visits of these subjects. The results show an average CoMiSS of 11 at the first visit. After a therapeutic dietary intervention, the score at the second visit, which happened 3 weeks ± 5 days after the first one, dropped to an average value of 4. A satisfaction questionnaire completed by the primary care practitioners suggested an overall high level of satisfaction with the application of the CoMiSS tool in routine practice. These data highlight a huge discrepancy in the diagnosis and management of infants suspected of CMA in the different countries. The findings suggest that the CoMISS questionnaire is an effective tool in aiding awareness of CMPA in primary health care.
Immuno flow s r o 12843 Prague Czech Republic
Nestlé Health Science 1800 Vevey Switzerland
Olgahospital Zentrum für Kinder Jugend und Frauenmedizin Klinikum Stuttgart 70174 Stuttgart Germany
Sandwell and West Birmingham Hospitals Birmingham B18 7QH UK
Vrije Universiteit Brussel UZ Brussel KidZ Health Castle 1090 Brussels Belgium
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