INTRODUCTION: The purpose of this study is to identify the role of diabetes mellitus in the effectiveness of intradialytic exercise intervention among haemodialysis patients. METHODS: In this multicentre study 90 dialysed patients were allocated to the experimental (EXG, n=57) or control group (CNG, n=33). In EXG, we included 20 diabetic and 37 non-diabetic patients. In CNG, we enrolled 8 diabetic and 25 non-diabetic patients. EXG underwent a 12-week supervised, progressive, intradialytic resistance training programme, while CNG stayed inactive during dialysis. Baseline, post-interventional and post-follow-up assessments of maximal force during hip extension (HE), hip flexion (HF) and knee extension (KE) contractions were completed in both groups of patients. RESULTS: HE increased in diabetic and non-diabetic EXG patients (diabetic EXG, change: +14.5N; 95% CI=-5.5 to +34.5; non-diabetic EXG, +18.6N; 95% CI=+3.4 to +33.8) and diabetic CNG patients (change: +17.9N; 95% CI=-9.2 to +44.9). Only non-diabetic CNG patients experienced a decrease in HE (change: -22.8N; 95% CI=-36.9 to -8.7, P<.05). CONCLUSIONS: Resistance training improved muscle function among dialysis patients regardless of the presence of diabetes mellitus. We found that non-diabetic patients lose their muscle function extensively during inactivity, while diabetic patients retain their muscle function.

Clinic of Internal Medicine 1 Comenius University Bratislava Slovakia

Department of Health Psychology and Research Methodology Faculty of Medicine Pavol Jozef Safarik University Kosice Slovakia

Department of Health Psychology and Research Methodology Faculty of Medicine Pavol Jozef Safarik University Kosice Slovakia; Olomouc University Society and Health Institute Palacky University Olomouc Olomouc Czech Republic; 2nd Department of Internal Medicine Faculty of Medicine Pavol Jozef Safarik University Kosice Slovakia; Fresenius Medical Care Dialysis Services Kosice Kosice Slovakia

Department of Health Psychology and Research Methodology Faculty of Medicine Pavol Jozef Safarik University Kosice Slovakia; Olomouc University Society and Health Institute Palacky University Olomouc Olomouc Czech Republic; Department of Community and Occupational Medicine University Medical Center Groningen University of Groningen Groningen Netherlands

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Age and sex differences in the effectiveness of intradialytic resistance training on muscle function