Department of Laboratory Medicine University of California San Francisco

Department of Physiology College of Osteopathic Medicine Michigan State University East Lansing

Institute of Physiology of the Czech Academy of Sciences Prague Czech Republic

798–808 PubMed

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Song J, Brown M, Cobb L, Jacobson M, Ide N, MacGregor G, He F. Implementation of the finalized sodium targets in the US is projected to save over 400,000 lives by 2031. Hypertension. 2022; 79:798–808. doi: 10.1161/HYPERTENSIONAHA.121.18475 PubMed

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Kurtz TW, DiCarlo SE, Pravenec M, Ježek F, Šilar J, Kofránek J, Morris RC, Jr. Testing computer models predicting human responses to a high-salt diet. Hypertension. 2018; 72:1407–1416. doi: 10.1161/HYPERTENSIONAHA.118.11552 PubMed PMC

Cook NR, He FJ, MacGregor GA, Graudal N. Sodium and health-concordance and controversy. BMJ. 2020; 369:m2440. doi: 10.1136/bmj.m2440 PubMed PMC

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Gressier M, Sassi F, Frost G. Contribution of reformulation, product renewal, and changes in consumer behavior to the reduction of salt intakes in the UK population between 2008/2009 and 2016/2017. Am J Clin Nutr. 2021; 114:1092–1099. doi: 10.1093/ajcn/nqab130 PubMed PMC

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Alonso S, Tan M, Wang C, Kent S, Cobiac L, MacGregor GA, He FJ, Mihaylova B. Impact of the 2003 to 2018 population salt intake reduction program in England: a modeling study. Hypertension. 2021; 77:1086–1094. doi: 10.1161/HYPERTENSIONAHA.120.16649 PubMed PMC

He FJ, Tan M, Ma Y, MacGregor GA. Salt reduction to prevent hypertension and cardiovascular disease: JACC state-of-the-art review. J Am Coll Cardiol. 2020; 75:632–647. doi: 10.1016/j.jacc.2019.11.055 PubMed

Kurtz TW, Pravenec M, DiCarlo SE. Strategies are needed to prevent salt-induced hypertension that do not depend on reducing salt intake. Am J Hypertens. 2020; 33:116–118. doi: 10.1093/ajh/hpz173 PubMed PMC

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Charlton KE, Corso B, Ware L, Schutte AE, Wepener L, Minicuci N, Naidoo N, Kowal P. Effect of South Africa’s interim mandatory salt reduction programme on urinary sodium excretion and blood pressure. Prev Med Rep. 2021; 23:101469. doi: 10.1016/j.pmedr.2021.101469 PubMed PMC

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Morris RC, Jr, Pravenec M, Silhavy J, DiCarlo SE, Kurtz TW. Small amounts of inorganic nitrate or beetroot provide substantial protection from salt-induced increases in blood pressure. Hypertension. 2019; 73:1042–1048. doi: 10.1161/hypertensionaha.118.12234 PubMed PMC

Mechanism-based strategies to prevent salt sensitivity and salt-induced hypertension