Invasive Aspergillus infection of middle ear in a patient treated with secukinumab, methotrexate, and corticosteroids for psoriasis and psoriatic arthritis
Jazyk angličtina Země Anglie, Velká Británie Médium print-electronic
Typ dokumentu kazuistiky, časopisecké články
- Klíčová slova
- Aspergillosis, anti-IL-17, psoriasis, psoriatic arthritis, secukinumab,
- MeSH
- aspergilóza * etiologie komplikace MeSH
- dospělí MeSH
- hormony kůry nadledvin MeSH
- lidé MeSH
- methotrexát terapeutické užití MeSH
- psoriatická artritida * komplikace farmakoterapie MeSH
- psoriáza * farmakoterapie komplikace MeSH
- střední ucho MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- Názvy látek
- hormony kůry nadledvin MeSH
- methotrexát MeSH
- secukinumab MeSH Prohlížeč
Mucocutaneous mycotic infections are common complications in patients on IL-17 inhibitor therapy. We report a case of a 33-year-old male with severe psoriasis and psoriatic arthritis on secukinumab combined with methotrexate and prednisone with swelling, otorrhea, and pain of the right ear and external auditory canal. Due to progressive hypacusis, a surgical solution was chosen. Tissue samples taken during surgery revealed the presence of Aspergillus fumigatus. Aspergillosis should be suspected in prolonged otorrhea, especially in immunocompromised patients. Without intervention, the disease could be fatal.
Department of Radiology University Hospital Hradec Králové Hradec Králové Czech Republic
Department of Rheumatology Revma Praha Prague Czech Republic
Citace poskytuje Crossref.org
