Outcome of Cataract Surgery in Patients With Retinitis Pigmentosa
Language English Country United States Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
36252678
DOI
10.1016/j.ajo.2022.10.001
PII: S0002-9394(22)00389-0
Knihovny.cz E-resources
- MeSH
- Adult MeSH
- Phacoemulsification * MeSH
- Lens Implantation, Intraocular MeSH
- Cataract * complications MeSH
- Middle Aged MeSH
- Humans MeSH
- Retinitis Pigmentosa * complications diagnosis surgery MeSH
- Retrospective Studies MeSH
- Aged MeSH
- Capsule Opacification * MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Aged MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
PURPOSE: To assess the visual outcome of cataract surgery in patients with retinitis pigmentosa (RP). DESIGN: Retrospective, noncomparative clinical study. METHODS: Preoperative, intraoperative, and postoperative data of patients with RP who were undergoing cataract surgery were collected from several expertise centers across Europe. RESULTS: In total, 295 eyes of 226 patients were included in the study. The mean age at surgery of the first eye was 56.1 ± 17.9 years. Following surgery, best-corrected visual acuity (BCVA) improved significantly from 1.03 to 0.81 logMAR (ie, 20/214 to 20/129 Snellen) in the first treated eye (-0.22 logMAR; 95% CI = -0.31 to -0.13; P < .001) and from 0.80 to 0.56 logMAR (ie, 20/126 to 20/73 Snellen) in the second treated eye (-0.24 logMAR; 95% CI = -0.32 to -0.15; P < .001). Marked BCVA improvements (postoperative change in BCVA of ≥0.3 logMAR) were observed in 87 of 226 patients (39%). Greater odds for marked visual improvements were observed in patients with moderate visual impairment or worse. The most common complications were zonular dialysis (n = 15; 5%) and (exacerbation of) cystoid macular edema (n = 14; 5%), respectively. Postoperative posterior capsular opacifications were present in 111 of 295 eyes (38%). CONCLUSION: Significant improvements in BCVA are observed in most patients with RP following cataract surgery. Baseline BCVA is a predictor of visual outcome. Preoperative evaluation should include the assessment of potential zonular insufficiency and the presence of CME, as they are relatively common and may increase the risk of complications.
Department of Ophthalmology Erasmus University Medical Center Rotterdam Netherlands
Department of Ophthalmology Erasmus University Medical Center Rotterdam Rotterdam Netherlands
Department of Ophthalmology Ghent Ghent University and Ghent University Hospital Ghent Belgium
Department of Ophthalmology Ghent University and Ghent University Hospital Ghent Belgium
Department of Ophthalmology Leeds Teaching Hospitals NHS Trust Leeds United Kingdom
Department of Ophthalmology Lithuanian University of Health Sciences Kaunas Lithuania
Department of Ophthalmology Radboud University Medical Center Nijmegen Netherlands
Department of Ophthalmology University of Basel Basel Switzerland
From the Department of Ophthalmology Amsterdam University Medical Centers Amsterdam Netherlands
From the Department of Ophthalmology Leiden University Medical Center Leiden Netherlands
Mathematical Institute Leiden University Medical Center Leiden Netherlands
Novartis Institute of BioMedical Research Harvard Medical School Boston Massachusetts USA
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