Baseline immunophenotypic profile of bone marrow leukemia cells in acute myeloid leukemia with nucleophosmin-1 gene mutation: a EuroFlow study
Jazyk angličtina Země Spojené státy americké Médium electronic
Typ dokumentu dopisy, práce podpořená grantem
PubMed
37666856
PubMed Central
PMC10477264
DOI
10.1038/s41408-023-00909-4
PII: 10.1038/s41408-023-00909-4
Knihovny.cz E-zdroje
- MeSH
- akutní myeloidní leukemie * genetika MeSH
- kostní dřeň MeSH
- lidé MeSH
- mutace MeSH
- nukleofosmin * MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- dopisy MeSH
- práce podpořená grantem MeSH
- Názvy látek
- nukleofosmin * MeSH
Department of Hematology Complejo Asistencial de Ávila Ávila Spain
Department of Hematology Complejo Asistencial de Zamora Zamora Spain
Department of Hematology Complejo Asistencial Universitario de León León Spain
Department of Hematology Complejo Asistencial Universitario de Palencia Palencia Spain
Department of Hematology Hospital Clínico Universitario de Valladolid Valladolid Spain
Department of Hematology Hospital Universitario de Burgos Burgos Spain
Department of Immunology Erasmus MC University Medical Center Rotterdam Rotterdam The Netherlands
Department of Immunology Leiden University Medical Center Leiden The Netherlands
Dutch Childhood Oncology Group The Hague The Netherlands
FACS Stem Cell Laboratory Kantonsspital Aarau Aarau Switzerland
Hematology Department University Hospital of Salamanca CIBERONC Salamanca Spain
Hematology Service Hospital Clinic Barcelona Spain
Hematology Service University Hospital of Getafe Madrid Spain
Pathology Service Hospital del Mar Barcelona Spain
Translational and Clinical Research Program Centro de Investigación del Cáncer Salamanca Spain
Zobrazit více v PubMed
Falini B, Martelli MP, Pileri SA, Mecucci C. Molecular and alternative methods for diagnosis of acute myeloid leukemia with mutated NPM1: flexibility may help. Haematologica. 2010;95:529–34. doi: 10.3324/haematol.2009.017822. PubMed DOI PMC
Falini B, Martelli MP, Bolli N, Bonasso R, Ghia E, Pallotta MT, et al. Immunohistochemistry predicts nucleophosmin (NPM) mutations in acute myeloid leukemia. Blood. 2006;108:1999–2005. doi: 10.1182/blood-2006-03-007013. PubMed DOI
Park BG, Chi H-S, Jang S, Park C-J, Kim D-Y, Lee J-H, et al. Association of cup-like nuclei in blasts with FLT3 and NPM1 mutations in acute myeloid leukemia. Ann Hematol. 2013;92:451–7. doi: 10.1007/s00277-012-1645-5. PubMed DOI
Mason EF, Hasserjian RP, Aggarwal N, Seegmiller AC, Pozdnyakova O. Blast phenotype and comutations in acute myeloid leukemia with mutated NPM1 influence disease biology and outcome. Blood Adv. 2019;3:3322–32. doi: 10.1182/bloodadvances.2019000328. PubMed DOI PMC
Woolthuis CM, Mulder AB, Verkaik-Schakel RN, Rosati S, Diepstra A, van den Berg E, et al. A single center analysis of nucleophosmin in acute myeloid leukemia: value of combining immunohistochemistry with molecular mutation analysis. Haematologica. 2013;98:1532–8. doi: 10.3324/haematol.2012.079806. PubMed DOI PMC
Angelini DF, Ottone T, Guerrera G, Lavorgna S, Cittadini M, Buccisano F, et al. A leukemia-associated CD34/CD123/CD25/CD99+ immunophenotype identifies FLT3-mutated clones in acute myeloid leukemia. Clin Cancer Res. 2015;21:3977–85. doi: 10.1158/1078-0432.CCR-14-3186. PubMed DOI
Mer AS, Heath EM, Madani Tonekaboni SA, Dogan-Artun N, Nair SK, Murison A, et al. Biological and therapeutic implications of a unique subtype of NPM1 mutated AML. Nat Commun. 2021;12:1054. doi: 10.1038/s41467-021-21233-0. PubMed DOI PMC
Martelli MP, Pettirossi V, Thiede C, Bonifacio E, Mezzasoma F, Cecchini D, et al. CD34+ cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice. Blood. 2010;116:3907–22. doi: 10.1182/blood-2009-08-238899. PubMed DOI
Pianigiani G, Rocchio F, Peruzzi S, Andresen V, Bigerna B, Sorcini D, et al. The absent/low expression of CD34 in NPM1-mutated AML is not related to cytoplasmic dislocation of NPM1 mutant protein. Leukemia. 2022;36:1931–4. 10.1038/s41375-022-01593-2. PubMed PMC
Brunetti L, Gundry MC, Sorcini D, Guzman AG, Huang Y-H, Ramabadran R, et al. Mutant NPM1 maintains the leukemic state through HOX expression. Cancer Cell. 2018;34:499–512.e9. doi: 10.1016/j.ccell.2018.08.005. PubMed DOI PMC
Matarraz S, Almeida J, Flores-Montero J, Lécrevisse Q, Guerri V, López A, et al. Introduction to the diagnosis and classification of monocytic-lineage leukemias by flow. Cytom B Clin Cytom. 2017;92:218–27. doi: 10.1002/cyto.b.21219. PubMed DOI
Wang AJ, Han Y, Jia N, Chen P, Minden MD. NPM1c impedes CTCF functions through cytoplasmic mislocalization in acute myeloid leukemia. Leukemia. 2020;34:1278–90. doi: 10.1038/s41375-019-0681-8. PubMed DOI
Gu X, Ebrahem Q, Mahfouz RZ, Hasipek M, Enane F, Radivoyevitch T, et al. Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates. J Clin Invest. 2018; 128:4260–79. PubMed PMC
Dawson MA, Gudgin EJ, Horton SJ, Giotopoulos G, Meduri E, Robson S, et al. Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia. Leukemia. 2014;28:311–20. doi: 10.1038/leu.2013.338. PubMed DOI PMC
Abdellateif MS, Kassem AB, El-Meligui YM. Combined expression of CD34 and FLT3-internal tandem duplication mutation predicts poor response to treatment in acute myeloid leukemia. Int J Gen Med. 2020;13:867–79. doi: 10.2147/IJGM.S276138. PubMed DOI PMC