Introduction of continuous glucose monitoring (CGM) is a key factor in decreasing HbA1c in war refugee children with type 1 diabetes
Jazyk angličtina Země Irsko Médium print-electronic
Typ dokumentu pozorovací studie, časopisecké články
Odkazy
PubMed
38309536
DOI
10.1016/j.diabres.2024.111118
PII: S0168-8227(24)00031-7
Knihovny.cz E-zdroje
- Klíčová slova
- Children, Continuous glucose monitoring, Diabetes management, HbA1c, Type 1 diabetes, War refugees,
- MeSH
- diabetes mellitus 1. typu * farmakoterapie MeSH
- dítě MeSH
- glykovaný hemoglobin MeSH
- kontinuální monitorování glukózy MeSH
- krevní glukóza MeSH
- lidé MeSH
- selfmonitoring glykemie MeSH
- uprchlíci * MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- pozorovací studie MeSH
- Názvy látek
- glykovaný hemoglobin MeSH
- krevní glukóza MeSH
AIMS: Our aim was to describe the changes in therapy and diabetes control in Ukrainian war refugee children with diabetes (CwD) during the first year of their stay in Czechia. METHODS: A total of 124 CwD (62 male, 62 female) were enrolled into this observational study. Anthropometric, laboratory and diabetes management data were acquired at baseline and at 3 months intervals for 12 months. All CwD were offered a CGM device during their first visit. Generalized Estimating Equation models were fitted in order to estimate the dynamics of studied characteristics. RESULTS: Median baseline HbA1c was 58 mmol/mol (IQR [48; 73]mmol/mol) (7.5 %, IQR[6.5;8.8]%). The HbA1c decreased significantly throughout the course of the study at a pace of - 2.2 mmol/mol (-0.2 %pt.) per visit (P = 0.01, CI[-3.2;-1.1]). The pace of the decrease in the average HbA1c was significantly higher in the group of CwD who received CGM in Czechia than in those who already had it from Ukraine by 2.9 mmol/mol (0.27 %pt.) per visit (P < 0.001, CI [-4.4; -1.3]). CONCLUSIONS: The steepest decrease in HbA1c was observed in CwD with newly initiated CGM underlining its vital role in improving the glucose control of CwD regardless of their background.
Department of Pediatrics Ceske Budejovice Hospital Ceske Budejovice Czech Republic
Department of Pediatrics Masaryk Hospital Usti nad Labem Czech Republic
Department of Pediatrics University Hospital Brno Brno Czech Republic
Department of Pediatrics University Hospital Hradec Kralove Hradec Kralove Czech Republic
Department of Pediatrics University Hospital Olomouc Olomouc Czech Republic
Department of Pediatrics University Hospital Ostrava Ostrava Czech Republic
Department of Pediatrics University Hospital Pilsen Pilsen Czech Republic
Faculty of Medicine Charles University Prague Czech Republic