Large-scale biorepositories and databases are essential to generate equitable, effective, and sustainable advances in cancer prevention, early detection, cancer therapy, cancer care, and surveillance. The Mutographs project has created a large genomic dataset and biorepository of over 7,800 cancer cases from 30 countries across five continents with extensive demographic, lifestyle, environmental, and clinical information. Whole-genome sequencing is being finalized for over 4,000 cases, with the primary goal of understanding the causes of cancer at eight anatomic sites. Genomic, exposure, and clinical data will be publicly available through the International Cancer Genome Consortium Accelerating Research in Genomic Oncology platform. The Mutographs sample and metadata biorepository constitutes a legacy resource for new projects and collaborations aiming to increase our current research efforts in cancer genomic epidemiology globally.

Associação de Combate ao Câncer em Goiás Hospital Araújo Jorge Goiânia Goiânia Brazil

Brazilian National Cancer Institute Rio de Janeiro Brazil

Cancer Ageing and Somatic Mutation Wellcome Sanger Institute Cambridge UK

Cancer Research Center Cancer Institute Tehran University of Medical Sciences Tehran Iran

Centro di Riferimento Oncologico di Aviano IRCCS Aviano Italy

Clinical Epidemiology N N Blokhin National Medical Research Centre of Oncology Moscow Russia

Department of Cancer Epidemiology and Genetics Masaryk Memorial Cancer Institute Brno Czech Republic

Department of Cellular and Molecular Medicine University of California San Diego La Jolla CA USA; Department of Bioengineering University of California San Diego La Jolla CA USA; Moores Cancer Center University of California San Diego La Jolla CA USA

Department of Environmental Epidemiology Nofer Institute of Occupational Medicine Łódź Poland

Department of Epidemiology A C Camargo Cancer Center São Paulo Brazil

Department of Epidemiology A C Camargo Cancer Center São Paulo Brazil; University of São Paulo Medical School São Paulo Brazil

Department of Internal Medicine Chiang Mai University Chiang Mai Thailand

Department of Pathology Radboud University Medical Centre Nijmegen the Netherlands

Department of Surgery Santa Casa School of Medicine São Paulo Brazil

Department of Urology University Hospital Center Zagreb Zagreb Croatia; University of Zagreb School of Medicine Zagreb Croatia

Departments of Surgery and Oncology McGill University Montreal QC Canada

Digestive Disease Research Institute Tehran University of Medical Sciences Tehran Iran

Division of Cancer Epidemiology and Genetics National Cancer Institute National Institutes of Health Rockville MD USA

Division of Cancer Epidemiology and Genetics National Cancer Institute Rockville MD USA

Division of Epidemiology Department of Quantitative Health Sciences Mayo Clinic Jacksonville FL USA; Division of Gastroenterology and Hepatology Department of Internal Medicine Mayo Clinic Jacksonville FL USA

Division of Molecular Epidemiology and Population Genomics Centre for Cancer Epidemiology Tata Memorial Centre Mumbai India

Early Cancer Institute University of Cambridge Cambridge UK

Environment and Lifestyle Epidemiology Branch International Agency for Research on Cancer Lyon France

Evidence Synthesis and Classification Branch International Agency for Research on Cancer Lyon France

Experimental Research Center Genomic Medicine Laboratory Hospital de Clínicas de Porto Alegre Porto Alegre Brazil; Post Graduate Program in Genetics and Molecular Biology Universidade Federal do Rio Grande do Sul Porto Alegre Brazil

Faculty of Health Sciences Palacky University Olomouc Czech Republic

Genomic Epidemiology Branch International Agency for Research on Cancer Lyon France

Hellenic Cooperative Oncology Group Athens Greece

Hospital Santa Rita AFECC Associação Feminina de Educação e Combate ao Câncer Vitoria Brazil

Institute of Public Health and Preventive Medicine 2nd Faculty of Medicine Charles University Prague Czech Republic; Department of Oncology 2nd Faculty of Medicine Charles University and Motol University Hospital Prague Czech Republic

Instituto de Oncología Angel Roffo Universidad de Buenos Aires Buenos Aires Argentina

Instituto Medicina Traslacional e Ingenieria Biomedica CONICET Buenos Aires Argentina

IOCPR International Organization for Cancer Prevention and Research Serbia Belgrade

Kilimanjaro Clinical Research Institute Kilimanjaro Christian Medical Centre and Kilimanjaro Christian Medical University College Moshi Tanzania

Laboratory of Genetic Diagnostic National Cancer Institute Vilnius Lithuania; Department of Botany and Genetics Institute of Biosciences Vilnius University Vilnius Lithuania

Laboratory of Molecular Medicine The Institute of Medical Science The University of Tokyo Minato ku Japan; Division of Cancer Genomics National Cancer Center Research Institute Chuo ku Japan

Leeds Institute of Medical Research at St James's University of Leeds Leeds UK

Moi University School of Public Health Eldoret Kenya

Molecular Medicine Center Department of Medical Chemistry and Biochemistry Medical Faculty Medical University of Sofia Sofia Bulgaria

Molecular Oncology Research Center Barretos Cancer Hospital Barretos Brazil

Molecular Oncology Research Center Barretos Cancer Hospital Barretos Brazil; Life and Health Sciences Research Institute School of Medicine Minho University Braga Portugal

Mount Sinai Hospital; Ontario Institute for Cancer Research Toronto ON Canada

National and Kapodistrian University of Athens Athens Greece

National Cancer Institute Bangkok Thailand

National Cancer Institute Bogotá Colombia

National Cancer Institute Kiev Ukraine

Observational and Pragmatic Research Institute Pte Ltd Singapore Singapore

Occupational Health and Toxicology National Center for Environmental Risk Monitoring National Institute of Public Health Bucharest Romania

Ontario Tumour Bank Ontario Institute for Cancer Research Toronto ON Canada

Pathology Department Hospital Universitario Fundación Santa Fe de Bogotá Bogotá Colombia

Regional Authority of Public Health Banská Bystrica Slovakia

Semmelweis University Budapest Hungary

The Maria Sklodowska Cure National Research Institute of Oncology Warsaw Poland

Translational Medicine Research Center Faculty of Medicine Prince of Songkla University Hat Yai Thailand

Unit of Biostatistics Epidemiology and Public Health Department of Cardio Thoraco Vascular Sciences and Public Health University of Padua Padova Italy

University Health Network Toronto ON Canada

University of Malawi College of Medicine Blantyre Malawi

Urology Department Carol Davila University of Medicine and Pharmacy Prof Dr Th Burghele Clinical Hospital Bucharest Romania

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